Wengel J - Search Results

1

Locked nucleic acid nucleoside triphosphates and polymerases: on the way towards evolution of LNA aptamers.

Veedu RN, Wengel J. Veedu RN, et al. Among authors: wengel j. Mol Biosyst. 2009 Aug;5(8):787-92. doi: 10.1039/b905513b. Epub 2009 May 15. Mol Biosyst. 2009. PMID: 19603111 Review.

2

The first analogues of LNA (locked nucleic acids): phosphorothioate-LNA and 2'-thio-LNA.

Kumar R, Singh SK, Koshkin AA, Rajwanshi VK, Meldgaard M, Wengel J. Kumar R, et al. Among authors: wengel j. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2219-22. doi: 10.1016/s0960-894x(98)00366-7. Bioorg Med Chem Lett. 1998. PMID: 9873516

3

The solution structure of a locked nucleic acid (LNA) hybridized to DNA.

Nielsen CB, Singh SK, Wengel J, Jacobsen JP. Nielsen CB, et al. Among authors: wengel j. J Biomol Struct Dyn. 1999 Oct;17(2):175-91. doi: 10.1080/07391102.1999.10508352. J Biomol Struct Dyn. 1999. PMID: 10563569

4

The conformations of locked nucleic acids (LNA).

Petersen M, Nielsen CB, Nielsen KE, Jensen GA, Bondensgaard K, Singh SK, Rajwanshi VK, Koshkin AA, Dahl BM, Wengel J, Jacobsen JP. Petersen M, et al. Among authors: wengel j. J Mol Recognit. 2000 Jan-Feb;13(1):44-53. doi: 10.1002/(SICI)1099-1352(200001/02)13:1<44::AID-JMR486>3.0.CO;2-6. J Mol Recognit. 2000. PMID: 10679896

5

Synthesis of abasic locked nucleic acid and two seco-LNA derivatives and evaluation of their hybridization properties compared with their more flexible DNA counterparts.

Kvaernø L, Kumar R, Dahl BM, Olsen CE, Wengel J. Kvaernø L, et al. Among authors: wengel j. J Org Chem. 2000 Aug 25;65(17):5167-76. doi: 10.1021/jo000275x. J Org Chem. 2000. PMID: 10993342

6

The adenine derivative of alpha-L-LNA (alpha-L-ribo configured locked nucleic acid): synthesis and high-affinity hybridization towards DNA, RNA, LNA and alpha-L-LNA complementary sequences.

Håkansson AE, Wengel J. Håkansson AE, et al. Among authors: wengel j. Bioorg Med Chem Lett. 2001 Apr 9;11(7):935-8. doi: 10.1016/s0960-894x(01)00110-x. Bioorg Med Chem Lett. 2001. PMID: 11294395

7

LNA (locked nucleic acid) and the diastereoisomeric alpha-L-LNA: conformational tuning and high-affinity recognition of DNA/RNA targets.

Wengel J, Petersen M, Nielsen KE, Jensen GA, Håkansson AE, Kumar R, Sørensen MD, Rajwanshi VK, Bryld T, Jacobsen JP. Wengel J, et al. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):389-96. doi: 10.1081/NCN-100002312. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563053

8

Locked nucleic acid (LNA) recognition of RNA: NMR solution structures of LNA:RNA hybrids.

Petersen M, Bondensgaard K, Wengel J, Jacobsen JP. Petersen M, et al. Among authors: wengel j. J Am Chem Soc. 2002 May 29;124(21):5974-82. doi: 10.1021/ja012288d. J Am Chem Soc. 2002. PMID: 12022830

9

Methylphosphonate LNA: a locked nucleic acid with a methylphosphonate linkage.

Lauritsen A, Dahl BM, Dahl O, Vester B, Wengel J. Lauritsen A, et al. Among authors: wengel j. Bioorg Med Chem Lett. 2003 Jan 20;13(2):253-6. doi: 10.1016/s0960-894x(02)00882-x. Bioorg Med Chem Lett. 2003. PMID: 12482433

10

alpha-L-LNA (alpha-L-ribo configured locked nucleic acid) recognition of DNA: an NMR spectroscopic study.

Nielsen KM, Petersen M, Håkansson AE, Wengel J, Jacobsen JP. Nielsen KM, et al. Among authors: wengel j. Chemistry. 2002 Jul 2;8(13):3001-9. doi: 10.1002/1521-3765(20020703)8:13<3001::AID-CHEM3001>3.0.CO;2-1. Chemistry. 2002. PMID: 12489231

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