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Pioglitazone, a PPARγ agonist, suppresses CYP19 transcription: evidence for involvement of 15-hydroxyprostaglandin dehydrogenase and BRCA1.
Subbaramaiah K, Howe LR, Zhou XK, Yang P, Hudis CA, Kopelovich L, Dannenberg AJ. Subbaramaiah K, et al. Among authors: yang p. Cancer Prev Res (Phila). 2012 Oct;5(10):1183-94. doi: 10.1158/1940-6207.CAPR-12-0201. Epub 2012 Jul 10. Cancer Prev Res (Phila). 2012. Retraction in: Cancer Prev Res (Phila). 2022 Jun 2;15(6):411. doi: 10.1158/1940-6207.CAPR-22-0204 PMID: 22787115 Free PMC article. Retracted.
Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland.
Subbaramaiah K, Howe LR, Bhardwaj P, Du B, Gravaghi C, Yantiss RK, Zhou XK, Blaho VA, Hla T, Yang P, Kopelovich L, Hudis CA, Dannenberg AJ. Subbaramaiah K, et al. Among authors: yang p. Cancer Prev Res (Phila). 2011 Mar;4(3):329-46. doi: 10.1158/1940-6207.CAPR-10-0381. Cancer Prev Res (Phila). 2011. Retraction in: Cancer Prev Res (Phila). 2022 Jun 2;15(6):413. doi: 10.1158/1940-6207.CAPR-22-0202 PMID: 21372033 Free PMC article. Retracted.
15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.
Yan M, Myung SJ, Fink SP, Lawrence E, Lutterbaugh J, Yang P, Zhou X, Liu D, Rerko RM, Willis J, Dawson D, Tai HH, Barnholtz-Sloan JS, Newman RA, Bertagnolli MM, Markowitz SD. Yan M, et al. Among authors: yang p. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9409-13. doi: 10.1073/pnas.0902367106. Epub 2009 May 22. Proc Natl Acad Sci U S A. 2009. PMID: 19470469 Free PMC article. Clinical Trial.
Weight Loss and/or Sulindac Mitigate Obesity-associated Transcriptome, Microbiome, and Protumor Effects in a Murine Model of Colon Cancer.
Bowers LW, Glenny EM, Punjala A, Lanman NA, Goldbaum A, Himbert C, Montgomery SA, Yang P, Roper J, Ulrich CM, Dannenberg AJ, Coleman MF, Hursting SD. Bowers LW, et al. Among authors: yang p. Cancer Prev Res (Phila). 2022 Aug 1;15(8):481-495. doi: 10.1158/1940-6207.CAPR-21-0531. Cancer Prev Res (Phila). 2022. PMID: 35653548 Free PMC article.
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