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Page 1
Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.
Sekiya M, Yahagi N, Tamura Y, Okazaki H, Igarashi M, Ohta K, Takanashi M, Kumagai M, Takase S, Nishi M, Takeuchi Y, Izumida Y, Kubota M, Ohashi K, Iizuka Y, Yagyu H, Gotoda T, Nagai R, Shimano H, Yamada N, Kadowaki T, Ishibashi S, Osuga J. Sekiya M, et al. Among authors: nagai r. Biochem Biophys Res Commun. 2009 Sep 25;387(3):511-5. doi: 10.1016/j.bbrc.2009.07.078. Epub 2009 Jul 18. Biochem Biophys Res Commun. 2009. PMID: 19619509
Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice.
Sekiya M, Osuga J, Okazaki H, Yahagi N, Harada K, Shen WJ, Tamura Y, Tomita S, Iizuka Y, Ohashi K, Okazaki M, Sata M, Nagai R, Fujita T, Shimano H, Kraemer FB, Yamada N, Ishibashi S. Sekiya M, et al. Among authors: nagai r. J Biol Chem. 2004 Apr 9;279(15):15084-90. doi: 10.1074/jbc.M310985200. Epub 2004 Jan 28. J Biol Chem. 2004. PMID: 14752112 Free article.
In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression.
Takeuchi Y, Yahagi N, Nakagawa Y, Matsuzaka T, Shimizu R, Sekiya M, Iizuka Y, Ohashi K, Gotoda T, Yamamoto M, Nagai R, Kadowaki T, Yamada N, Osuga J, Shimano H. Takeuchi Y, et al. Among authors: nagai r. Biochem Biophys Res Commun. 2007 Nov 16;363(2):329-35. doi: 10.1016/j.bbrc.2007.08.165. Epub 2007 Sep 6. Biochem Biophys Res Commun. 2007. PMID: 17880923 Free article.
Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis.
Sekiya M, Osuga J, Yahagi N, Okazaki H, Tamura Y, Igarashi M, Takase S, Harada K, Okazaki S, Iizuka Y, Ohashi K, Yagyu H, Okazaki M, Gotoda T, Nagai R, Kadowaki T, Shimano H, Yamada N, Ishibashi S. Sekiya M, et al. Among authors: nagai r. J Lipid Res. 2008 Aug;49(8):1829-38. doi: 10.1194/jlr.M800198-JLR200. Epub 2008 May 14. J Lipid Res. 2008. PMID: 18480494 Free article.
Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.
Sekiya M, Osuga J, Nagashima S, Ohshiro T, Igarashi M, Okazaki H, Takahashi M, Tazoe F, Wada T, Ohta K, Takanashi M, Kumagai M, Nishi M, Takase S, Yahagi N, Yagyu H, Ohashi K, Nagai R, Kadowaki T, Furukawa Y, Ishibashi S. Sekiya M, et al. Among authors: nagai r. Cell Metab. 2009 Sep;10(3):219-28. doi: 10.1016/j.cmet.2009.08.004. Cell Metab. 2009. PMID: 19723498 Free article.
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.
Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N. Yahagi N, et al. Among authors: nagai r. J Biol Chem. 2002 May 31;277(22):19353-7. doi: 10.1074/jbc.M201584200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923308 Free article.
Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.
Okazaki H, Osuga J, Tsukamoto K, Isoo N, Kitamine T, Tamura Y, Tomita S, Sekiya M, Yahagi N, Iizuka Y, Ohashi K, Harada K, Gotoda T, Shimano H, Kimura S, Nagai R, Yamada N, Ishibashi S. Okazaki H, et al. Among authors: nagai r. J Biol Chem. 2002 Aug 30;277(35):31893-9. doi: 10.1074/jbc.M204016200. Epub 2002 May 29. J Biol Chem. 2002. PMID: 12036961 Free article.
p53 Activation in adipocytes of obese mice.
Yahagi N, Shimano H, Matsuzaka T, Najima Y, Sekiya M, Nakagawa Y, Ide T, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Gotoda T, Nagai R, Kimura S, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: nagai r. J Biol Chem. 2003 Jul 11;278(28):25395-400. doi: 10.1074/jbc.M302364200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12734185 Free article.
Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver.
Okazaki H, Tazoe F, Okazaki S, Isoo N, Tsukamoto K, Sekiya M, Yahagi N, Iizuka Y, Ohashi K, Kitamine T, Tozawa R, Inaba T, Yagyu H, Okazaki M, Shimano H, Shibata N, Arai H, Nagai RZ, Kadowaki T, Osuga J, Ishibashi S. Okazaki H, et al. Among authors: nagai rz. J Lipid Res. 2006 Sep;47(9):1950-8. doi: 10.1194/jlr.M600224-JLR200. Epub 2006 Jun 1. J Lipid Res. 2006. PMID: 16741291 Free article.
1,797 results