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Benzo[c][2,7]naphthyridines as inhibitors of PDK-1.
Bioorg Med Chem Lett. 2009 Sep 1;19(17):5225-8. doi: 10.1016/j.bmcl.2009.07.007. Epub 2009 Jul 8.
Bioorg Med Chem Lett. 2009.
PMID: 19628388
4-(Phenylaminomethylene)isoquinoline-1,3(2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4 (CDK4).
Tsou HR, Otteng M, Tran T, Floyd MB Jr, Reich M, Birnberg G, Kutterer K, Ayral-Kaloustian S, Ravi M, Nilakantan R, Grillo M, McGinnis JP, Rabindran SK.
Tsou HR, et al. Among authors: floyd mb jr.
J Med Chem. 2008 Jun 26;51(12):3507-25. doi: 10.1021/jm800072z.
J Med Chem. 2008.
PMID: 18494457
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4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile inhibitors of epidermal growth factor receptor kinase and their bioisosteric relationship to the 4-anilino-6,7-dialkoxyquinazoline inhibitors.
Wissner A, Berger DM, Boschelli DH, Floyd MB Jr, Greenberger LM, Gruber BC, Johnson BD, Mamuya N, Nilakantan R, Reich MF, Shen R, Tsou HR, Upeslacis E, Wang YF, Wu B, Ye F, Zhang N.
Wissner A, et al. Among authors: floyd mb jr.
J Med Chem. 2000 Aug 24;43(17):3244-56. doi: 10.1021/jm000206a.
J Med Chem. 2000.
PMID: 10966743
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Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with in vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785).
Discafani CM, Carroll ML, Floyd MB Jr, Hollander IJ, Husain Z, Johnson BD, Kitchen D, May MK, Malo MS, Minnick AA Jr, Nilakantan R, Shen R, Wang YF, Wissner A, Greenberger LM.
Discafani CM, et al. Among authors: floyd mb jr.
Biochem Pharmacol. 1999 Apr 15;57(8):917-25. doi: 10.1016/s0006-2952(98)00356-6.
Biochem Pharmacol. 1999.
PMID: 10086326
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