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Page 1
Perianal disease, small bowel disease, smoking, prior steroid or early azathioprine/biological therapy are predictors of disease behavior change in patients with Crohn's disease.
Lakatos PL, Czegledi Z, Szamosi T, Banai J, David G, Zsigmond F, Pandur T, Erdelyi Z, Gemela O, Papp J, Lakatos L. Lakatos PL, et al. Among authors: gemela o. World J Gastroenterol. 2009 Jul 28;15(28):3504-10. doi: 10.3748/wjg.15.3504. World J Gastroenterol. 2009. PMID: 19630105 Free PMC article.
Early azathioprine/biological therapy is associated with decreased risk for first surgery and delays time to surgery but not reoperation in both smokers and nonsmokers with Crohn's disease, while smoking decreases the risk of colectomy in ulcerative colitis.
Szamosi T, Banai J, Lakatos L, Czegledi Z, David G, Zsigmond F, Pandur T, Erdelyi Z, Gemela O, Papp M, Papp J, Lakatos PL. Szamosi T, et al. Among authors: gemela o. Eur J Gastroenterol Hepatol. 2010 Jul;22(7):872-9. doi: 10.1097/MEG.0b013e32833036d9. Eur J Gastroenterol Hepatol. 2010. PMID: 19648821
New serological markers for inflammatory bowel disease are associated with earlier age at onset, complicated disease behavior, risk for surgery, and NOD2/CARD15 genotype in a Hungarian IBD cohort.
Papp M, Altorjay I, Dotan N, Palatka K, Foldi I, Tumpek J, Sipka S, Udvardy M, Dinya T, Lakatos L, Kovacs A, Molnar T, Tulassay Z, Miheller P, Norman GL, Szamosi T, Papp J; Hungarian IBD Study Group; Lakatos PL. Papp M, et al. Am J Gastroenterol. 2008 Mar;103(3):665-81. doi: 10.1111/j.1572-0241.2007.01652.x. Epub 2007 Nov 28. Am J Gastroenterol. 2008. PMID: 18047543