Tsao DH - Search Results

1

Backbone and side-chain assignment of the lipidated and non-lipidated forms of the meningococcal outer membrane protein LP2086.

Mascioni A, Jacob J, Moy F, Dilts D, Fink P, Malakian K, Sigethy S, Wen Y, Novikova E, Zlotnick GW, Tsao DH. Mascioni A, et al. Among authors: tsao dh. Biomol NMR Assign. 2009 Jun;3(1):111-3. doi: 10.1007/s12104-009-9153-9. Epub 2009 Mar 5. Biomol NMR Assign. 2009. PMID: 19636959

2

Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway.

Tsao DH, McDonagh T, Telliez JB, Hsu S, Malakian K, Xu GY, Lin LL. Tsao DH, et al. Mol Cell. 2000 Jun;5(6):1051-7. doi: 10.1016/s1097-2765(00)80270-1. Mol Cell. 2000. PMID: 10911999 Free article.

3

Fragment-based drug design.

Feyfant E, Cross JB, Paris K, Tsao DH. Feyfant E, et al. Among authors: tsao dh. Methods Mol Biol. 2011;685:241-52. doi: 10.1007/978-1-60761-931-4_12. Methods Mol Biol. 2011. PMID: 20981527

4

Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid (PSI-421), a P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury.

Huang A, Moretto A, Janz K, Lowe M, Bedard PW, Tam S, Di L, Clerin V, Sushkova N, Tchernychev B, Tsao DH, Keith JC, Shaw GD, Schaub RG, Wang Q, Kaila N. Huang A, et al. Among authors: tsao dh. J Med Chem. 2010 Aug 26;53(16):6003-17. doi: 10.1021/jm9013696. J Med Chem. 2010. PMID: 20718494

5

Identification and characterization of acidic mammalian chitinase inhibitors.

Cole DC, Olland AM, Jacob J, Brooks J, Bursavich MG, Czerwinski R, DeClercq C, Johnson M, Joseph-McCarthy D, Ellingboe JW, Lin L, Nowak P, Presman E, Strand J, Tam A, Williams CM, Yao S, Tsao DH, Fitz LJ. Cole DC, et al. Among authors: tsao dh. J Med Chem. 2010 Aug 26;53(16):6122-8. doi: 10.1021/jm100533p. J Med Chem. 2010. PMID: 20666458

6

Novel synthesis and structural characterization of a high-affinity paramagnetic kinase probe for the identification of non-ATP site binders by nuclear magnetic resonance.

Moy FJ, Lee A, Gavrin LK, Xu ZB, Sievers A, Kieras E, Stochaj W, Mosyak L, McKew J, Tsao DH. Moy FJ, et al. Among authors: tsao dh. J Med Chem. 2010 Feb 11;53(3):1238-49. doi: 10.1021/jm901525b. J Med Chem. 2010. PMID: 20038108

7

NMR dynamics and antibody recognition of the meningococcal lipidated outer membrane protein LP2086 in micellar solution.

Mascioni A, Moy FJ, McNeil LK, Murphy E, Bentley BE, Camarda R, Dilts DA, Fink PS, Gusarova V, Hoiseth SK, Malakian K, Mininni T, Novikova E, Lin S, Sigethy S, Zlotnick GW, Tsao DH. Mascioni A, et al. Among authors: tsao dh. Biochim Biophys Acta. 2010 Feb;1798(2):87-93. doi: 10.1016/j.bbamem.2009.09.021. Epub 2009 Oct 14. Biochim Biophys Acta. 2010. PMID: 19835839 Free article.

8

Structural Basis for the Immunogenic Properties of the Meningococcal Vaccine Candidate LP2086.

Mascioni A, Bentley BE, Camarda R, Dilts DA, Fink P, Gusarova V, Hoiseth SK, Jacob J, Lin SL, Malakian K, McNeil LK, Mininni T, Moy F, Murphy E, Novikova E, Sigethy S, Wen Y, Zlotnick GW, Tsao DH. Mascioni A, et al. Among authors: tsao dh. J Biol Chem. 2009 Mar 27;284(13):8738-46. doi: 10.1074/jbc.M808831200. Epub 2008 Dec 22. J Biol Chem. 2009. PMID: 19103601 Free PMC article.

9

Identification, characterization and initial hit-to-lead optimization of a series of 4-arylamino-3-pyridinecarbonitrile as protein kinase C theta (PKCtheta) inhibitors.

Cole DC, Asselin M, Brennan A, Czerwinski R, Ellingboe JW, Fitz L, Greco R, Huang X, Joseph-McCarthy D, Kelly MF, Kirisits M, Lee J, Li Y, Morgan P, Stock JR, Tsao DH, Wissner A, Yang X, Chaudhary D. Cole DC, et al. Among authors: tsao dh. J Med Chem. 2008 Oct 9;51(19):5958-63. doi: 10.1021/jm800214a. Epub 2008 Sep 11. J Med Chem. 2008. PMID: 18783200

10

Solution structure of wild-type human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor.

Markus MA, Dwyer B, Wolfrom S, Li J, Li W, Malakian K, Wilhelm J, Tsao DH. Markus MA, et al. Among authors: tsao dh. J Biomol NMR. 2008 May;41(1):55-60. doi: 10.1007/s10858-008-9236-4. Epub 2008 Apr 19. J Biomol NMR. 2008. PMID: 18425585 No abstract available.

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