Dooley S - Search Results

1

YB-1 acts as a ligand for Notch-3 receptors and modulates receptor activation.

Rauen T, Raffetseder U, Frye BC, Djudjaj S, Mühlenberg PJ, Eitner F, Lendahl U, Bernhagen J, Dooley S, Mertens PR. Rauen T, et al. Among authors: dooley s. J Biol Chem. 2009 Sep 25;284(39):26928-40. doi: 10.1074/jbc.M109.046599. Epub 2009 Jul 29. J Biol Chem. 2009. PMID: 19640841 Free PMC article.

2

Participation of Smad2, Smad3, and Smad4 in transforming growth factor beta (TGF-beta)-induced activation of Smad7. THE TGF-beta response element of the promoter requires functional Smad binding element and E-box sequences for transcriptional regulation.

Stopa M, Anhuf D, Terstegen L, Gatsios P, Gressner AM, Dooley S. Stopa M, et al. Among authors: dooley s. J Biol Chem. 2000 Sep 22;275(38):29308-17. doi: 10.1074/jbc.M003282200. J Biol Chem. 2000. PMID: 10887185 Free article.

3

The effects of platelet-derived growth factor antagonism in experimental glomerulonephritis are independent of the transforming growth factor-beta system.

Ostendorf T, Kunter U, van Roeyen C, Dooley S, Janjic N, Ruckman J, Eitner F, Floege J. Ostendorf T, et al. Among authors: dooley s. J Am Soc Nephrol. 2002 Mar;13(3):658-667. doi: 10.1681/ASN.V133658. J Am Soc Nephrol. 2002. PMID: 11856769

4

Y-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effects.

Dooley S, Said HM, Gressner AM, Floege J, En-Nia A, Mertens PR. Dooley S, et al. J Biol Chem. 2006 Jan 20;281(3):1784-95. doi: 10.1074/jbc.M510215200. Epub 2005 Nov 8. J Biol Chem. 2006. PMID: 16278212 Free article.

5

Id1 is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells.

Wiercinska E, Wickert L, Denecke B, Said HM, Hamzavi J, Gressner AM, Thorikay M, ten Dijke P, Mertens PR, Breitkopf K, Dooley S. Wiercinska E, et al. Among authors: dooley s. Hepatology. 2006 May;43(5):1032-41. doi: 10.1002/hep.21135. Hepatology. 2006. PMID: 16628634

6

IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads.

Weng H, Mertens PR, Gressner AM, Dooley S. Weng H, et al. Among authors: dooley s. J Hepatol. 2007 Feb;46(2):295-303. doi: 10.1016/j.jhep.2006.09.014. Epub 2006 Nov 3. J Hepatol. 2007. PMID: 17125875

7

Polymeric meshes induce zonal regulation of matrix metalloproteinase-2 gene expression by macrophages and fibroblasts.

Jansen PL, Kever M, Rosch R, Krott E, Jansen M, Alfonso-Jaume A, Dooley S, Klinge U, Lovett DH, Mertens PR. Jansen PL, et al. Among authors: dooley s. FASEB J. 2007 Apr;21(4):1047-57. doi: 10.1096/fj.06-6755com. Epub 2007 Jan 10. FASEB J. 2007. PMID: 17215487

8

Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice.

Hamzavi J, Ehnert S, Godoy P, Ciuclan L, Weng H, Mertens PR, Heuchel R, Dooley S. Hamzavi J, et al. Among authors: dooley s. J Cell Mol Med. 2008 Oct;12(5B):2130-44. doi: 10.1111/j.1582-4934.2008.00262.x. Epub 2008 Feb 4. J Cell Mol Med. 2008. PMID: 18266971 Free PMC article.

9

Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage.

Dooley S, Hamzavi J, Ciuclan L, Godoy P, Ilkavets I, Ehnert S, Ueberham E, Gebhardt R, Kanzler S, Geier A, Breitkopf K, Weng H, Mertens PR. Dooley S, et al. Gastroenterology. 2008 Aug;135(2):642-59. doi: 10.1053/j.gastro.2008.04.038. Epub 2008 May 15. Gastroenterology. 2008. PMID: 18602923 Free article.

10

Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen.

Frye BC, Halfter S, Djudjaj S, Muehlenberg P, Weber S, Raffetseder U, En-Nia A, Knott H, Baron JM, Dooley S, Bernhagen J, Mertens PR. Frye BC, et al. Among authors: dooley s. EMBO Rep. 2009 Jul;10(7):783-9. doi: 10.1038/embor.2009.81. Epub 2009 May 29. EMBO Rep. 2009. PMID: 19483673 Free PMC article.

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