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Page 1
2-Aminobenzimidazoles as potent Aurora kinase inhibitors.
Zhong M, Bui M, Shen W, Baskaran S, Allen DA, Elling RA, Flanagan WM, Fung AD, Hanan EJ, Harris SO, Heumann SA, Hoch U, Ivy SN, Jacobs JW, Lam S, Lee H, McDowell RS, Oslob JD, Purkey HE, Romanowski MJ, Silverman JA, Tangonan BT, Taverna P, Yang W, Yoburn JC, Yu CH, Zimmerman KM, O'Brien T, Lew W. Zhong M, et al. Among authors: baskaran s. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5158-61. doi: 10.1016/j.bmcl.2009.07.016. Epub 2009 Jul 9. Bioorg Med Chem Lett. 2009. PMID: 19646866
Tethering identifies fragment that yields potent inhibitors of human caspase-1.
Fahr BT, O'Brien T, Pham P, Waal ND, Baskaran S, Raimundo BC, Lam JW, Sopko MM, Purkey HE, Romanowski MJ. Fahr BT, et al. Among authors: baskaran s. Bioorg Med Chem Lett. 2006 Feb;16(3):559-62. doi: 10.1016/j.bmcl.2005.10.048. Epub 2005 Nov 4. Bioorg Med Chem Lett. 2006. PMID: 16274992
Discovery of a potent and selective aurora kinase inhibitor.
Oslob JD, Romanowski MJ, Allen DA, Baskaran S, Bui M, Elling RA, Flanagan WM, Fung AD, Hanan EJ, Harris S, Heumann SA, Hoch U, Jacobs JW, Lam J, Lawrence CE, McDowell RS, Nannini MA, Shen W, Silverman JA, Sopko MM, Tangonan BT, Teague J, Yoburn JC, Yu CH, Zhong M, Zimmerman KM, O'Brien T, Lew W. Oslob JD, et al. Among authors: baskaran s. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4880-4. doi: 10.1016/j.bmcl.2008.07.073. Epub 2008 Jul 24. Bioorg Med Chem Lett. 2008. PMID: 18678489
Water-soluble prodrugs of an Aurora kinase inhibitor.
Oslob JD, Heumann SA, Yu CH, Allen DA, Baskaran S, Bui M, Delarosa E, Fung AD, Hashash A, Hau J, Ivy S, Jacobs JW, Lew W, Maung J, McDowell RS, Ritchie S, Romanowski MJ, Silverman JA, Yang W, Zhong M, Fuchs-Knotts T. Oslob JD, et al. Among authors: baskaran s. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1409-12. doi: 10.1016/j.bmcl.2009.01.043. Epub 2009 Jan 19. Bioorg Med Chem Lett. 2009. PMID: 19186057
Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization.
Shotwell JB, Baskaran S, Chong P, Creech KL, Crosby RM, Dickson H, Fang J, Garrido D, Mathis A, Maung J, Parks DJ, Pouliot JJ, Price DJ, Rai R, Seal JW 3rd, Schmitz U, Tai VW, Thomson M, Xie M, Xiong ZZ, Peat AJ. Shotwell JB, et al. Among authors: baskaran s. ACS Med Chem Lett. 2012 May 24;3(7):565-9. doi: 10.1021/ml300090x. eCollection 2012 Jul 12. ACS Med Chem Lett. 2012. PMID: 24900511 Free PMC article.
Design and synthesis of dimeric heparinoid mimetics.
Rele SM, Iyer SS, Baskaran S, Chaikof EL. Rele SM, et al. Among authors: baskaran s. J Org Chem. 2004 Dec 24;69(26):9159-70. doi: 10.1021/jo049092r. J Org Chem. 2004. PMID: 15609950
206 results