Alvarez R - Search Results

1

Isocombretastatins A: 1,1-diarylethenes as potent inhibitors of tubulin polymerization and cytotoxic compounds.

Alvarez R, Alvarez C, Mollinedo F, Sierra BG, Medarde M, Peláez R. Alvarez R, et al. Among authors: alvarez c. Bioorg Med Chem. 2009 Sep 1;17(17):6422-31. doi: 10.1016/j.bmc.2009.07.012. Epub 2009 Jul 9. Bioorg Med Chem. 2009. PMID: 19647439

2

1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity.

Alvarez R, Velázquez S, San-Félix A, Aquaro S, De Clercq E, Perno CF, Karlsson A, Balzarini J, Camarasa MJ. Alvarez R, et al. J Med Chem. 1994 Nov 25;37(24):4185-94. doi: 10.1021/jm00050a015. J Med Chem. 1994. PMID: 7527463

3

Synthesis and anti-HIV activity of [AZT]-[TSAO-T] and [AZT]-[HEPT] dimers as potential multifunctional inhibitors of HIV-1 reverse transcriptase.

Velázquez S, Alvarez R, San-Félix A, Jimeno ML, De Clercq E, Balzarini J, Camarasa MJ. Velázquez S, et al. Among authors: alvarez r. J Med Chem. 1995 May 12;38(10):1641-9. doi: 10.1021/jm00010a008. J Med Chem. 1995. PMID: 7538589

4

Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase.

Velázquez S, Chamorro C, Pérez-Pérez MJ, Alvarez R, Jimeno ML, Martín-Domenech A, Pérez C, Gago F, De Clercq E, Balzarini J, San-Félix A, Camarasa MJ. Velázquez S, et al. Among authors: alvarez r. J Med Chem. 1998 Nov 5;41(23):4636-47. doi: 10.1021/jm980370m. J Med Chem. 1998. PMID: 9804703 Free article.

5

Synthesis and biological activity of naphthalene analogues of phenstatins: naphthylphenstatins.

Alvarez C, Alvarez R, Corchete P, Pérez-Melero C, Peláez R, Medarde M. Alvarez C, et al. Among authors: alvarez r. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3417-20. doi: 10.1016/j.bmcl.2007.03.082. Epub 2007 Mar 30. Bioorg Med Chem Lett. 2007. PMID: 17434303

6

Conformationally restricted macrocyclic analogues of combretastatins.

Mateo C, Alvarez R, Pérez-Melero C, Peláez R, Medarde M. Mateo C, et al. Among authors: alvarez r. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6316-20. doi: 10.1016/j.bmcl.2007.08.075. Epub 2007 Sep 4. Bioorg Med Chem Lett. 2007. PMID: 17889536

7

Diarylmethyloxime and hydrazone derivatives with 5-indolyl moieties as potent inhibitors of tubulin polymerization.

Alvarez C, Alvarez R, Corchete P, López JL, Pérez-Melero C, Peláez R, Medarde M. Alvarez C, et al. Among authors: alvarez r. Bioorg Med Chem. 2008 Jun 1;16(11):5952-61. doi: 10.1016/j.bmc.2008.04.054. Epub 2008 Apr 26. Bioorg Med Chem. 2008. PMID: 18502133

8

Naphthylphenstatins as tubulin ligands: synthesis and biological evaluation.

Alvarez C, Alvarez R, Corchete P, Pérez-Melero C, Peláez R, Medarde M. Alvarez C, et al. Among authors: alvarez r. Bioorg Med Chem. 2008 Oct 1;16(19):8999-9008. doi: 10.1016/j.bmc.2008.08.040. Epub 2008 Aug 26. Bioorg Med Chem. 2008. PMID: 18790642

9

Exploring the effect of 2,3,4-trimethoxy-phenyl moiety as a component of indolephenstatins.

Alvarez C, Alvarez R, Corchete P, Pérez-Melero C, Peláez R, Medarde M. Alvarez C, et al. Among authors: alvarez r. Eur J Med Chem. 2010 Feb;45(2):588-97. doi: 10.1016/j.ejmech.2009.10.047. Epub 2009 Nov 3. Eur J Med Chem. 2010. PMID: 19939521

10

New para-para stilbenophanes: synthesis by McMurry coupling, conformational analysis and inhibition of tubulin polymerisation.

Álvarez R, López V, Mateo C, Medarde M, Peláez R. Álvarez R, et al. Chemistry. 2011 Mar 14;17(12):3406-19. doi: 10.1002/chem.201002869. Epub 2011 Feb 23. Chemistry. 2011. PMID: 21344518

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