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Protein ISGylation modulates the JAK-STAT signaling pathway.
Malakhova OA, Yan M, Malakhov MP, Yuan Y, Ritchie KJ, Kim KI, Peterson LF, Shuai K, Zhang DE. Malakhova OA, et al. Among authors: yan m. Genes Dev. 2003 Feb 15;17(4):455-60. doi: 10.1101/gad.1056303. Genes Dev. 2003. PMID: 12600939 Free PMC article.
Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.
Zhou GB, Kang H, Wang L, Gao L, Liu P, Xie J, Zhang FX, Weng XQ, Shen ZX, Chen J, Gu LJ, Yan M, Zhang DE, Chen SJ, Wang ZY, Chen Z. Zhou GB, et al. Among authors: yan m. Blood. 2007 Apr 15;109(8):3441-50. doi: 10.1182/blood-2006-06-032250. Epub 2006 Dec 29. Blood. 2007. PMID: 17197433 Free PMC article.
7,186 results