Markusic DM - Search Results

1

Tolerance induction to cytoplasmic beta-galactosidase by hepatic AAV gene transfer: implications for antigen presentation and immunotoxicity.

Martino AT, Nayak S, Hoffman BE, Cooper M, Liao G, Markusic DM, Byrne BJ, Terhorst C, Herzog RW. Martino AT, et al. Among authors: markusic dm. PLoS One. 2009 Aug 4;4(8):e6376. doi: 10.1371/journal.pone.0006376. PLoS One. 2009. PMID: 19652717 Free PMC article.

2

High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.

Markusic DM, Herzog RW, Aslanidi GV, Hoffman BE, Li B, Li M, Jayandharan GR, Ling C, Zolotukhin I, Ma W, Zolotukhin S, Srivastava A, Zhong L. Markusic DM, et al. Mol Ther. 2010 Dec;18(12):2048-56. doi: 10.1038/mt.2010.172. Epub 2010 Aug 24. Mol Ther. 2010. PMID: 20736929 Free PMC article.

3

The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver.

Martino AT, Suzuki M, Markusic DM, Zolotukhin I, Ryals RC, Moghimi B, Ertl HC, Muruve DA, Lee B, Herzog RW. Martino AT, et al. Among authors: markusic dm. Blood. 2011 Jun 16;117(24):6459-68. doi: 10.1182/blood-2010-10-314518. Epub 2011 Apr 7. Blood. 2011. PMID: 21474674 Free PMC article.

4

Induction of tolerance to factor VIII by transient co-administration with rapamycin.

Moghimi B, Sack BK, Nayak S, Markusic DM, Mah CS, Herzog RW. Moghimi B, et al. Among authors: markusic dm. J Thromb Haemost. 2011 Aug;9(8):1524-33. doi: 10.1111/j.1538-7836.2011.04351.x. J Thromb Haemost. 2011. PMID: 21585650 Free PMC article.

5

AAV vector biology in primates: finding the missing link?

Herzog RW, Davidoff AM, Markusic DM, Nathwani AC. Herzog RW, et al. Among authors: markusic dm. Mol Ther. 2011 Nov;19(11):1923-4. doi: 10.1038/mt.2011.218. Mol Ther. 2011. PMID: 22051598 Free PMC article. No abstract available.

6

Transient B cell depletion or improved transgene expression by codon optimization promote tolerance to factor VIII in gene therapy.

Sack BK, Merchant S, Markusic DM, Nathwani AC, Davidoff AM, Byrne BJ, Herzog RW. Sack BK, et al. Among authors: markusic dm. PLoS One. 2012;7(5):e37671. doi: 10.1371/journal.pone.0037671. Epub 2012 May 24. PLoS One. 2012. PMID: 22655063 Free PMC article.

7

Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.

Martino AT, Basner-Tschakarjan E, Markusic DM, Finn JD, Hinderer C, Zhou S, Ostrov DA, Srivastava A, Ertl HC, Terhorst C, High KA, Mingozzi F, Herzog RW. Martino AT, et al. Among authors: markusic dm. Blood. 2013 Mar 21;121(12):2224-33. doi: 10.1182/blood-2012-10-460733. Epub 2013 Jan 16. Blood. 2013. PMID: 23325831 Free PMC article.

8

Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia.

Markusic DM, Herzog RW. Markusic DM, et al. J Genet Syndr Gene Ther. 2012 Jan 18;1:1-9. doi: 10.4172/2157-7412.S1-009. J Genet Syndr Gene Ther. 2012. PMID: 23565343 Free PMC article.

9

Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies.

Markusic DM, Hoffman BE, Perrin GQ, Nayak S, Wang X, LoDuca PA, High KA, Herzog RW. Markusic DM, et al. EMBO Mol Med. 2013 Nov;5(11):1698-709. doi: 10.1002/emmm.201302859. Epub 2013 Sep 16. EMBO Mol Med. 2013. PMID: 24106230 Free PMC article.

10

A David promoter with Goliath strength.

Markusic DM, Herzog RW. Markusic DM, et al. Blood. 2014 May 15;123(20):3068-9. doi: 10.1182/blood-2014-04-565507. Blood. 2014. PMID: 24832942 Free article.

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