Cerniglia GJ - Search Results

1

Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy.

Cerniglia GJ, Pore N, Tsai JH, Schultz S, Mick R, Choe R, Xing X, Durduran T, Yodh AG, Evans SM, Koch CJ, Hahn SM, Quon H, Sehgal CM, Lee WM, Maity A. Cerniglia GJ, et al. PLoS One. 2009 Aug 6;4(8):e6539. doi: 10.1371/journal.pone.0006539. PLoS One. 2009. PMID: 19657384 Free PMC article.

2

EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms.

Pore N, Jiang Z, Gupta A, Cerniglia G, Kao GD, Maity A. Pore N, et al. Cancer Res. 2006 Mar 15;66(6):3197-204. doi: 10.1158/0008-5472.CAN-05-3090. Cancer Res. 2006. PMID: 16540671

3

Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy.

Pore N, Gupta AK, Cerniglia GJ, Jiang Z, Bernhard EJ, Evans SM, Koch CJ, Hahn SM, Maity A. Pore N, et al. Among authors: cerniglia gj. Cancer Res. 2006 Sep 15;66(18):9252-9. doi: 10.1158/0008-5472.CAN-06-1239. Cancer Res. 2006. PMID: 16982770

4

HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells.

Pore N, Gupta AK, Cerniglia GJ, Maity A. Pore N, et al. Among authors: cerniglia gj. Neoplasia. 2006 Nov;8(11):889-95. doi: 10.1593/neo.06535. Neoplasia. 2006. PMID: 17132220 Free PMC article.

5

Farnesyltransferase inhibitor effects on prostate tumor micro-environment and radiation survival.

Shi Y, Wu J, Mick R, Cerniglia GJ, Cohen-Jonathan E, Rhim JS, Koch CJ, Bernhard EJ. Shi Y, et al. Among authors: cerniglia gj. Prostate. 2005 Jan 1;62(1):69-82. doi: 10.1002/pros.20122. Prostate. 2005. PMID: 15389805

6

The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response.

Gupta AK, Li B, Cerniglia GJ, Ahmed MS, Hahn SM, Maity A. Gupta AK, et al. Among authors: cerniglia gj. Neoplasia. 2007 Apr;9(4):271-8. doi: 10.1593/neo.07124. Neoplasia. 2007. PMID: 17460771 Free PMC article.

7

Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.

Jiang Z, Pore N, Cerniglia GJ, Mick R, Georgescu MM, Bernhard EJ, Hahn SM, Gupta AK, Maity A. Jiang Z, et al. Among authors: cerniglia gj. Cancer Res. 2007 May 1;67(9):4467-73. doi: 10.1158/0008-5472.CAN-06-3398. Cancer Res. 2007. PMID: 17483362

8

Dual PI3K/mTOR inhibitor NVP-BEZ235 suppresses hypoxia-inducible factor (HIF)-1α expression by blocking protein translation and increases cell death under hypoxia.

Karar J, Cerniglia GJ, Lindsten T, Koumenis C, Maity A. Karar J, et al. Among authors: cerniglia gj. Cancer Biol Ther. 2012 Sep;13(11):1102-11. doi: 10.4161/cbt.21144. Epub 2012 Aug 16. Cancer Biol Ther. 2012. PMID: 22895065 Free PMC article.

9

HIV protease inhibitors block Akt signaling and radiosensitize tumor cells both in vitro and in vivo.

Gupta AK, Cerniglia GJ, Mick R, McKenna WG, Muschel RJ. Gupta AK, et al. Among authors: cerniglia gj. Cancer Res. 2005 Sep 15;65(18):8256-65. doi: 10.1158/0008-5472.CAN-05-1220. Cancer Res. 2005. PMID: 16166302

10

Bortezomib sensitizes human head and neck carcinoma cells SQ20B to radiation.

Weber CN, Cerniglia GJ, Maity A, Gupta AK. Weber CN, et al. Among authors: cerniglia gj. Cancer Biol Ther. 2007 Feb;6(2):156-9. doi: 10.4161/cbt.6.2.3556. Epub 2007 Mar 1. Cancer Biol Ther. 2007. PMID: 17224644 Free article.

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