Gu Y - Search Results

1

Structure-Based Design of Anticancer Prodrug PABA/NO.

Ji X, Pal A, Kalathur R, Hu X, Gu Y, Saavedra JE, Buzard GS, Srinivasan A, Keefer LK, Singh SV. Ji X, et al. Among authors: gu y. Drug Des Devel Ther. 2008;2:123-130. doi: 10.2147/dddt.s3931. Drug Des Devel Ther. 2008. PMID: 19662104 Free PMC article.

2

Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide.

Gu Y, Xiao B, Wargo HL, Bucher MH, Singh SV, Ji X. Gu Y, et al. Biochemistry. 2003 Feb 4;42(4):917-21. doi: 10.1021/bi026778+. Biochemistry. 2003. PMID: 12549910

The crystal structure of mGSTA1-1 in complex with the GSH conjugate of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (GSBpd) reveals that R216 and I221 in the last helix play important roles in catalysis [Gu, Y., Singh, S. V., and Ji, X. (2000) B …

The crystal structure of mGSTA1-1 in complex with the GSH conjugate of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (GS …

3

Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity.

Gu Y, Guo J, Pal A, Pan SS, Zimniak P, Singh SV, Ji X. Gu Y, et al. Biochemistry. 2004 Dec 21;43(50):15673-9. doi: 10.1021/bi048757g. Biochemistry. 2004. PMID: 15595823

4

Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.

Gu Y, Reshetnikova L, Li Y, Wu Y, Yan H, Singh S, Ji X. Gu Y, et al. J Mol Biol. 2002 Jun 7;319(3):779-89. doi: 10.1016/S0022-2836(02)00339-X. J Mol Biol. 2002. PMID: 12054870

5

Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimic acid and an ATP analogue.

Gan J, Gu Y, Li Y, Yan H, Ji X. Gan J, et al. Among authors: gu y. Biochemistry. 2006 Jul 18;45(28):8539-45. doi: 10.1021/bi0606290. Biochemistry. 2006. PMID: 16834327

6

Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism.

Gan J, Wu Y, Prabakaran P, Gu Y, Li Y, Andrykovitch M, Liu H, Gong Y, Yan H, Ji X. Gan J, et al. Among authors: gu y. Biochemistry. 2007 Aug 21;46(33):9513-22. doi: 10.1021/bi602601e. Epub 2007 Jul 25. Biochemistry. 2007. PMID: 17649975

7

JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity.

Shami PJ, Saavedra JE, Wang LY, Bonifant CL, Diwan BA, Singh SV, Gu Y, Fox SD, Buzard GS, Citro ML, Waterhouse DJ, Davies KM, Ji X, Keefer LK. Shami PJ, et al. Among authors: gu y. Mol Cancer Ther. 2003 Apr;2(4):409-17. Mol Cancer Ther. 2003. PMID: 12700285

8

Characterization of four orthologs of stringent starvation protein A.

Andrykovitch M, Routzahn KM, Li M, Gu Y, Waugh DS, Ji X. Andrykovitch M, et al. Among authors: gu y. Acta Crystallogr D Biol Crystallogr. 2003 May;59(Pt 5):881-6. doi: 10.1107/s0907444903005699. Epub 2003 Apr 25. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12777805

9

Structural basis for the function of stringent starvation protein a as a transcription factor.

Hansen AM, Gu Y, Li M, Andrykovitch M, Waugh DS, Jin DJ, Ji X. Hansen AM, et al. Among authors: gu y. J Biol Chem. 2005 Apr 29;280(17):17380-91. doi: 10.1074/jbc.M501444200. Epub 2005 Feb 25. J Biol Chem. 2005. PMID: 15735307 Free article.

10

Crystallization and preliminary X-ray diffraction studies of NusG, a protein shared by the transcription and translation machines.

Andrykovitch M, Guo W, Routzahn KM, Gu Y, Anderson DE, Reshetnikova LS, Knowlton JR, Waugh DS, Ji X. Andrykovitch M, et al. Among authors: gu y. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2157-8. doi: 10.1107/s0907444902015810. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454485

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