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Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells.
Colland F, Formstecher E, Jacq X, Reverdy C, Planquette C, Conrath S, Trouplin V, Bianchi J, Aushev VN, Camonis J, Calabrese A, Borg-Capra C, Sippl W, Collura V, Boissy G, Rain JC, Guedat P, Delansorne R, Daviet L. Colland F, et al. Among authors: guedat p. Mol Cancer Ther. 2009 Aug;8(8):2286-95. doi: 10.1158/1535-7163.MCT-09-0097. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671755
Treatment with IFB-088 Improves Neuropathy in CMT1A and CMT1B Mice.
Bai Y, Treins C, Volpi VG, Scapin C, Ferri C, Mastrangelo R, Touvier T, Florio F, Bianchi F, Del Carro U, Baas FF, Wang D, Miniou P, Guedat P, Shy ME, D'Antonio M. Bai Y, et al. Among authors: guedat p. Mol Neurobiol. 2022 Jul;59(7):4159-4178. doi: 10.1007/s12035-022-02838-y. Epub 2022 Apr 30. Mol Neurobiol. 2022. PMID: 35501630 Free PMC article.
Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy.
Malerba A, Roth F, Harish P, Dhiab J, Lu-Nguyen N, Cappellari O, Jarmin S, Mahoudeau A, Ythier V, Lainé J, Negroni E, Abgueguen E, Simonelig M, Guedat P, Mouly V, Butler-Browne G, Voisset C, Dickson G, Trollet C. Malerba A, et al. Among authors: guedat p. Hum Mol Genet. 2019 May 15;28(10):1694-1708. doi: 10.1093/hmg/ddz007. Hum Mol Genet. 2019. PMID: 30649389
Control of the Unfolded Protein Response in Health and Disease.
Doultsinos D, Avril T, Lhomond S, Dejeans N, Guédat P, Chevet E. Doultsinos D, et al. Among authors: guedat p. SLAS Discov. 2017 Aug;22(7):787-800. doi: 10.1177/2472555217701685. Epub 2017 Apr 28. SLAS Discov. 2017. PMID: 28453376 Free article. Review.
Gemini surfactants: new synthetic vectors for gene transfection.
Kirby AJ, Camilleri P, Engberts JB, Feiters MC, Nolte RJ, Söderman O, Bergsma M, Bell PC, Fielden ML, García Rodríguez CL, Guédat P, Kremer A, McGregor C, Perrin C, Ronsin G, van Eijk MC. Kirby AJ, et al. Among authors: guedat p. Angew Chem Int Ed Engl. 2003 Apr 4;42(13):1448-57. doi: 10.1002/anie.200201597. Angew Chem Int Ed Engl. 2003. PMID: 12698476 Review.
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