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The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks.
Ali AAE, Timinszky G, Arribas-Bosacoma R, Kozlowski M, Hassa PO, Hassler M, Ladurner AG, Pearl LH, Oliver AW. Ali AAE, et al. Among authors: timinszky g. Nat Struct Mol Biol. 2012 Jun 10;19(7):685-692. doi: 10.1038/nsmb.2335. Nat Struct Mol Biol. 2012. PMID: 22683995 Free PMC article.
A family of macrodomain proteins reverses cellular mono-ADP-ribosylation.
Jankevicius G, Hassler M, Golia B, Rybin V, Zacharias M, Timinszky G, Ladurner AG. Jankevicius G, et al. Among authors: timinszky g. Nat Struct Mol Biol. 2013 Apr;20(4):508-14. doi: 10.1038/nsmb.2523. Epub 2013 Mar 10. Nat Struct Mol Biol. 2013. PMID: 23474712 Free PMC article.
Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease.
Sharifi R, Morra R, Appel CD, Tallis M, Chioza B, Jankevicius G, Simpson MA, Matic I, Ozkan E, Golia B, Schellenberg MJ, Weston R, Williams JG, Rossi MN, Galehdari H, Krahn J, Wan A, Trembath RC, Crosby AH, Ahel D, Hay R, Ladurner AG, Timinszky G, Williams RS, Ahel I. Sharifi R, et al. Among authors: timinszky g. EMBO J. 2013 May 2;32(9):1225-37. doi: 10.1038/emboj.2013.51. Epub 2013 Mar 12. EMBO J. 2013. PMID: 23481255 Free PMC article.
The recognition and removal of cellular poly(ADP-ribose) signals.
Barkauskaite E, Jankevicius G, Ladurner AG, Ahel I, Timinszky G. Barkauskaite E, et al. Among authors: timinszky g. FEBS J. 2013 Aug;280(15):3491-507. doi: 10.1111/febs.12358. Epub 2013 Jun 18. FEBS J. 2013. PMID: 23711178 Free article. Review.
PARP1 and CBP lose their footing in cancer.
Timinszky G, Ladurner AG. Timinszky G, et al. Nat Struct Mol Biol. 2014 Nov;21(11):947-8. doi: 10.1038/nsmb.2913. Nat Struct Mol Biol. 2014. PMID: 25372309 No abstract available.
35 results