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The synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pathway in CT-26 murine colorectal adenocarcinoma cells.
Chou LC, Yang JS, Huang LJ, Wu HC, Lu CC, Chiang JH, Chen KT, Kuo SC, Chung JG. Chou LC, et al. Among authors: wu hc. J Gastroenterol. 2009;44(10):1055-63. doi: 10.1007/s00535-009-0111-1. Epub 2009 Aug 14. J Gastroenterol. 2009. PMID: 19688288
KHC-4 anti-cancer effects on human PC3 prostate cancer cell line.
Hwang JM, Ting WJ, Wu HC, Chen YJ, Tsai FJ, Chen PY, Liu CY, Chou LC, Kuo SC, Huang CY. Hwang JM, et al. Among authors: wu hc. Am J Chin Med. 2012;40(5):1063-71. doi: 10.1142/S0192415X12500784. Am J Chin Med. 2012. PMID: 22928835
1,584 results