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15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expression.
Viita H, Markkanen J, Eriksson E, Nurminen M, Kinnunen K, Babu M, Heikura T, Turpeinen S, Laidinen S, Takalo T, Ylä-Herttuala S. Viita H, et al. Among authors: heikura t. Circ Res. 2008 Feb 1;102(2):177-84. doi: 10.1161/CIRCRESAHA.107.155556. Epub 2007 Nov 8. Circ Res. 2008. PMID: 17991885
Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer.
Tuppurainen L, Sallinen H, Kokki E, Koponen J, Anttila M, Pulkkinen K, Heikura T, Toivanen P, Hämäläinen K, Kosma VM, Heinonen S, Alitalo K, Ylä-Herttuala S. Tuppurainen L, et al. Among authors: heikura t. Hum Gene Ther Clin Dev. 2013 Mar;24(1):29-37. doi: 10.1089/humc.2013.006. Epub 2013 Apr 3. Hum Gene Ther Clin Dev. 2013. PMID: 23692381
Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart.
Rutanen J, Rissanen TT, Markkanen JE, Gruchala M, Silvennoinen P, Kivelä A, Hedman A, Hedman M, Heikura T, Ordén MR, Stacker SA, Achen MG, Hartikainen J, Ylä-Herttuala S. Rutanen J, et al. Among authors: heikura t. Circulation. 2004 Mar 2;109(8):1029-35. doi: 10.1161/01.CIR.0000115519.03688.A2. Epub 2004 Feb 16. Circulation. 2004. PMID: 14967735
46 results