Li TK - Search Results

1

Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification.

You QD, Li ZY, Huang CH, Yang Q, Wang XJ, Guo QL, Chen XG, He XG, Li TK, Chern JW. You QD, et al. Among authors: li zy, li tk. J Med Chem. 2009 Sep 24;52(18):5649-61. doi: 10.1021/jm900469e. J Med Chem. 2009. PMID: 19715319

2

5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity.

Ruchelman AL, Singh SK, Ray A, Wu XH, Yang JM, Li TK, Liu A, Liu LF, LaVoie EJ. Ruchelman AL, et al. Among authors: li tk. Bioorg Med Chem. 2003 May 1;11(9):2061-73. doi: 10.1016/s0968-0896(03)00051-8. Bioorg Med Chem. 2003. PMID: 12670657

3

Diaza- and triazachrysenes: potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435.

Ruchelman AL, Singh SK, Wu X, Ray A, Yang JM, Li TK, Liu A, Liu LF, LaVoie EJ. Ruchelman AL, et al. Among authors: li tk. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3333-6. doi: 10.1016/s0960-894x(02)00737-0. Bioorg Med Chem Lett. 2002. PMID: 12392745

4

Substituted dibenzo[c,h]cinnolines: topoisomerase I-targeting anticancer agents.

Yu Y, Singh SK, Liu A, Li TK, Liu LF, LaVoie EJ. Yu Y, et al. Among authors: li tk. Bioorg Med Chem. 2003 Apr 3;11(7):1475-91. doi: 10.1016/s0968-0896(02)00604-1. Bioorg Med Chem. 2003. PMID: 12628673

5

Substituted benzo[i]phenanthridines as mammalian topoisomerase-targeting agents.

Makhey D, Li D, Zhao B, Sim SP, Li TK, Liu A, Liu LF, LaVoie EJ. Makhey D, et al. Among authors: li d, li tk. Bioorg Med Chem. 2003 Apr 17;11(8):1809-20. doi: 10.1016/s0968-0896(03)00053-1. Bioorg Med Chem. 2003. PMID: 12659767

6

Nitro and amino substitution in the D-ring of 5-(2-dimethylaminoethyl)- 2,3-methylenedioxy-5H-dibenzo[c,h][1,6]naphthyridin-6-ones: effect on topoisomerase-I targeting activity and cytotoxicity.

Singh SK, Ruchelman AL, Li TK, Liu A, Liu LF, LaVoie EJ. Singh SK, et al. Among authors: li tk. J Med Chem. 2003 May 22;46(11):2254-7. doi: 10.1021/jm020498a. J Med Chem. 2003. PMID: 12747798

7

Nitro and amino substitution within the A-ring of 5H-8,9-dimethoxy-5-(2-N,N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: influence on topoisomerase I-targeting activity and cytotoxicity.

Ruchelman AL, Kerrigan JE, Li TK, Zhou N, Liu A, Liu LF, LaVoie EJ. Ruchelman AL, et al. Among authors: li tk. Bioorg Med Chem. 2004 Jul 1;12(13):3731-42. doi: 10.1016/j.bmc.2004.03.076. Bioorg Med Chem. 2004. PMID: 15186859

8

2,3-Dimethoxybenzo[i]phenanthridines: topoisomerase I-targeting anticancer agents.

Li D, Zhao B, Sim SP, Li TK, Liu A, Liu LF, LaVoie EJ. Li D, et al. Among authors: li tk. Bioorg Med Chem. 2003 Feb 20;11(4):521-8. doi: 10.1016/s0968-0896(02)00530-8. Bioorg Med Chem. 2003. PMID: 12538017

9

8,9-methylenedioxybenzo[i]phenanthridines: topoisomerase I-targeting activity and cytotoxicity.

Li D, Zhao B, Sim SP, Li TK, Liu A, Liu LF, LaVoie EJ. Li D, et al. Among authors: li tk. Bioorg Med Chem. 2003 Aug 15;11(17):3795-805. doi: 10.1016/s0968-0896(03)00394-8. Bioorg Med Chem. 2003. PMID: 12901925

10

Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates.

Hsin LW, Wang HP, Kao PH, Lee O, Chen WR, Chen HW, Guh JH, Chan YL, His CP, Yang MS, Li TK, Lee CH. Hsin LW, et al. Among authors: li tk. Bioorg Med Chem. 2008 Jan 15;16(2):1006-14. doi: 10.1016/j.bmc.2007.10.012. Epub 2007 Oct 10. Bioorg Med Chem. 2008. PMID: 17962028

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