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Page 1
Chemical genetic identification of peptidoglycan inhibitors potentiating carbapenem activity against methicillin-resistant Staphylococcus aureus.
Huber J, Donald RG, Lee SH, Jarantow LW, Salvatore MJ, Meng X, Painter R, Onishi RH, Occi J, Dorso K, Young K, Park YW, Skwish S, Szymonifka MJ, Waddell TS, Miesel L, Phillips JW, Roemer T. Huber J, et al. Among authors: phillips jw. Chem Biol. 2009 Aug 28;16(8):837-48. doi: 10.1016/j.chembiol.2009.05.012. Chem Biol. 2009. PMID: 19716474
Discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor by chemical-genetic profiling in Staphylococcus aureus.
Phillips JW, Goetz MA, Smith SK, Zink DL, Polishook J, Onishi R, Salowe S, Wiltsie J, Allocco J, Sigmund J, Dorso K, Lee S, Skwish S, de la Cruz M, Martín J, Vicente F, Genilloud O, Lu J, Painter RE, Young K, Overbye K, Donald RG, Singh SB. Phillips JW, et al. Chem Biol. 2011 Aug 26;18(8):955-65. doi: 10.1016/j.chembiol.2011.06.011. Chem Biol. 2011. PMID: 21867911
Coelomycin, a highly substituted 2,6-dioxo-pyrazine fungal metabolite antibacterial agent discovered by Staphylococcus aureus fitness test profiling.
Goetz MA, Zhang C, Zink DL, Arocho M, Vicente F, Bills GF, Polishook J, Dorso K, Onishi R, Gill C, Hickey E, Lee S, Ball R, Skwish S, Donald RG, Phillips JW, Singh SB. Goetz MA, et al. Among authors: phillips jw. J Antibiot (Tokyo). 2010 Aug;63(8):512-8. doi: 10.1038/ja.2010.86. Epub 2010 Jul 28. J Antibiot (Tokyo). 2010. PMID: 20664605
Broadening the spectrum of β-lactam antibiotics through inhibition of signal peptidase type I.
Therien AG, Huber JL, Wilson KE, Beaulieu P, Caron A, Claveau D, Deschamps K, Donald RG, Galgoci AM, Gallant M, Gu X, Kevin NJ, Lafleur J, Leavitt PS, Lebeau-Jacob C, Lee SS, Lin MM, Michels AA, Ogawa AM, Painter RE, Parish CA, Park YW, Benton-Perdomo L, Petcu M, Phillips JW, Powles MA, Skorey KI, Tam J, Tan CM, Young K, Wong S, Waddell ST, Miesel L. Therien AG, et al. Among authors: phillips jw. Antimicrob Agents Chemother. 2012 Sep;56(9):4662-70. doi: 10.1128/AAC.00726-12. Epub 2012 Jun 18. Antimicrob Agents Chemother. 2012. PMID: 22710113 Free PMC article.
Kibdelomycin A, a congener of kibdelomycin, derivatives and their antibacterial activities.
Singh SB, Goetz MA, Smith SK, Zink DL, Polishook J, Onishi R, Salowe S, Wiltsie J, Allocco J, Sigmund J, Dorso K, de la Cruz M, Martín J, Vicente F, Genilloud O, Donald RG, Phillips JW. Singh SB, et al. Among authors: phillips jw. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7127-30. doi: 10.1016/j.bmcl.2012.09.071. Epub 2012 Oct 2. Bioorg Med Chem Lett. 2012. PMID: 23084277
Isolation, structure elucidation and antibacterial activity of a new tetramic acid, ascosetin.
Ondeyka JG, Smith SK, Zink DL, Vicente F, Basilio A, Bills GF, Polishook JD, Garlisi C, Mcguinness D, Smith E, Qiu H, Gill CJ, Donald RG, Phillips JW, Goetz MA, Singh SB. Ondeyka JG, et al. Among authors: phillips jw. J Antibiot (Tokyo). 2014 Jul;67(7):527-31. doi: 10.1038/ja.2014.33. Epub 2014 Apr 2. J Antibiot (Tokyo). 2014. PMID: 24690911
141 results