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Generation of pluripotent stem cells from patients with type 1 diabetes.
Maehr R, Chen S, Snitow M, Ludwig T, Yagasaki L, Goland R, Leibel RL, Melton DA. Maehr R, et al. Among authors: leibel rl. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15768-73. doi: 10.1073/pnas.0906894106. Epub 2009 Aug 31. Proc Natl Acad Sci U S A. 2009. PMID: 19720998 Free PMC article.
iPSC-derived β cells model diabetes due to glucokinase deficiency.
Hua H, Shang L, Martinez H, Freeby M, Gallagher MP, Ludwig T, Deng L, Greenberg E, Leduc C, Chung WK, Goland R, Leibel RL, Egli D. Hua H, et al. Among authors: leibel rl. J Clin Invest. 2013 Jul;123(7):3146-53. doi: 10.1172/JCI67638. Epub 2013 Jun 17. J Clin Invest. 2013. Retraction in: J Clin Invest. 2017 Mar 1;127(3):1115. doi: 10.1172/JCI92775 PMID: 23778137 Free PMC article. Retracted.
Human oocytes reprogram somatic cells to a pluripotent state.
Noggle S, Fung HL, Gore A, Martinez H, Satriani KC, Prosser R, Oum K, Paull D, Druckenmiller S, Freeby M, Greenberg E, Zhang K, Goland R, Sauer MV, Leibel RL, Egli D. Noggle S, et al. Among authors: leibel rl. Nature. 2011 Oct 5;478(7367):70-5. doi: 10.1038/nature10397. Nature. 2011. PMID: 21979046
Differentiation of hypothalamic-like neurons from human pluripotent stem cells.
Wang L, Meece K, Williams DJ, Lo KA, Zimmer M, Heinrich G, Martin Carli J, Leduc CA, Sun L, Zeltser LM, Freeby M, Goland R, Tsang SH, Wardlaw SL, Egli D, Leibel RL. Wang L, et al. Among authors: leibel rl. J Clin Invest. 2015 Feb;125(2):796-808. doi: 10.1172/JCI79220. Epub 2015 Jan 2. J Clin Invest. 2015. PMID: 25555215 Free PMC article.
Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency.
González BJ, Zhao H, Niu J, Williams DJ, Lee J, Goulbourne CN, Xing Y, Wang Y, Oberholzer J, Blumenkrantz MH, Chen X, LeDuc CA, Chung WK, Colecraft HM, Gromada J, Shen Y, Goland RS, Leibel RL, Egli D. González BJ, et al. Among authors: leibel rl. Commun Biol. 2022 Aug 2;5(1):779. doi: 10.1038/s42003-022-03696-z. Commun Biol. 2022. PMID: 35918471 Free PMC article.
342 results