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107 results

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Page 1
Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.
Sekiya M, Osuga J, Nagashima S, Ohshiro T, Igarashi M, Okazaki H, Takahashi M, Tazoe F, Wada T, Ohta K, Takanashi M, Kumagai M, Nishi M, Takase S, Yahagi N, Yagyu H, Ohashi K, Nagai R, Kadowaki T, Furukawa Y, Ishibashi S. Sekiya M, et al. Among authors: osuga j. Cell Metab. 2009 Sep;10(3):219-28. doi: 10.1016/j.cmet.2009.08.004. Cell Metab. 2009. PMID: 19723498 Free article.
Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.
Okazaki H, Osuga J, Tsukamoto K, Isoo N, Kitamine T, Tamura Y, Tomita S, Sekiya M, Yahagi N, Iizuka Y, Ohashi K, Harada K, Gotoda T, Shimano H, Kimura S, Nagai R, Yamada N, Ishibashi S. Okazaki H, et al. Among authors: osuga j. J Biol Chem. 2002 Aug 30;277(35):31893-9. doi: 10.1074/jbc.M204016200. Epub 2002 May 29. J Biol Chem. 2002. PMID: 12036961 Free article.
Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis.
Sekiya M, Osuga J, Yahagi N, Okazaki H, Tamura Y, Igarashi M, Takase S, Harada K, Okazaki S, Iizuka Y, Ohashi K, Yagyu H, Okazaki M, Gotoda T, Nagai R, Kadowaki T, Shimano H, Yamada N, Ishibashi S. Sekiya M, et al. Among authors: osuga j. J Lipid Res. 2008 Aug;49(8):1829-38. doi: 10.1194/jlr.M800198-JLR200. Epub 2008 May 14. J Lipid Res. 2008. PMID: 18480494 Free article.
Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages.
Okazaki H, Igarashi M, Nishi M, Sekiya M, Tajima M, Takase S, Takanashi M, Ohta K, Tamura Y, Okazaki S, Yahagi N, Ohashi K, Amemiya-Kudo M, Nakagawa Y, Nagai R, Kadowaki T, Osuga J, Ishibashi S. Okazaki H, et al. Among authors: osuga j. J Biol Chem. 2008 Nov 28;283(48):33357-64. doi: 10.1074/jbc.M802686200. Epub 2008 Sep 9. J Biol Chem. 2008. PMID: 18782767 Free PMC article.
Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.
Sekiya M, Yahagi N, Tamura Y, Okazaki H, Igarashi M, Ohta K, Takanashi M, Kumagai M, Takase S, Nishi M, Takeuchi Y, Izumida Y, Kubota M, Ohashi K, Iizuka Y, Yagyu H, Gotoda T, Nagai R, Shimano H, Yamada N, Kadowaki T, Ishibashi S, Osuga J. Sekiya M, et al. Among authors: osuga j. Biochem Biophys Res Commun. 2009 Sep 25;387(3):511-5. doi: 10.1016/j.bbrc.2009.07.078. Epub 2009 Jul 18. Biochem Biophys Res Commun. 2009. PMID: 19619509
The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages.
Igarashi M, Osuga J, Uozaki H, Sekiya M, Nagashima S, Takahashi M, Takase S, Takanashi M, Li Y, Ohta K, Kumagai M, Nishi M, Hosokawa M, Fledelius C, Jacobsen P, Yagyu H, Fukayama M, Nagai R, Kadowaki T, Ohashi K, Ishibashi S. Igarashi M, et al. Among authors: osuga j. Circ Res. 2010 Nov 26;107(11):1387-95. doi: 10.1161/CIRCRESAHA.110.226613. Epub 2010 Oct 14. Circ Res. 2010. PMID: 20947831
Abrogation of neutral cholesterol ester hydrolytic activity causes adrenal enlargement.
Ohta K, Sekiya M, Uozaki H, Igarashi M, Takase S, Kumagai M, Takanashi M, Takeuchi Y, Izumida Y, Kubota M, Nishi M, Okazaki H, Iizuka Y, Yahagi N, Yagyu H, Fukayama M, Kadowaki T, Ohashi K, Ishibashi S, Osuga J. Ohta K, et al. Among authors: osuga j. Biochem Biophys Res Commun. 2011 Jan 7;404(1):254-60. doi: 10.1016/j.bbrc.2010.11.103. Epub 2010 Nov 25. Biochem Biophys Res Commun. 2011. PMID: 21111707
107 results