Doyle L - Search Results

1

High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.

Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM. Jarjour J, et al. Among authors: doyle l. Nucleic Acids Res. 2009 Nov;37(20):6871-80. doi: 10.1093/nar/gkp726. Epub 2009 Sep 8. Nucleic Acids Res. 2009. PMID: 19740766 Free PMC article.

2

De novo computational design of retro-aldol enzymes.

Jiang L, Althoff EA, Clemente FR, Doyle L, Röthlisberger D, Zanghellini A, Gallaher JL, Betker JL, Tanaka F, Barbas CF 3rd, Hilvert D, Houk KN, Stoddard BL, Baker D. Jiang L, et al. Among authors: doyle l. Science. 2008 Mar 7;319(5868):1387-91. doi: 10.1126/science.1152692. Science. 2008. PMID: 18323453 Free PMC article.

3

Comprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications.

Li H, Ulge UY, Hovde BT, Doyle LA, Monnat RJ Jr. Li H, et al. Nucleic Acids Res. 2012 Mar;40(6):2587-98. doi: 10.1093/nar/gkr1072. Epub 2011 Nov 25. Nucleic Acids Res. 2012. PMID: 22121229 Free PMC article.

4

Computational design of ligand-binding proteins with high affinity and selectivity.

Tinberg CE, Khare SD, Dou J, Doyle L, Nelson JW, Schena A, Jankowski W, Kalodimos CG, Johnsson K, Stoddard BL, Baker D. Tinberg CE, et al. Among authors: doyle l. Nature. 2013 Sep 12;501(7466):212-216. doi: 10.1038/nature12443. Epub 2013 Sep 4. Nature. 2013. PMID: 24005320 Free PMC article.

5

A synthetic sex ratio distortion system for the control of the human malaria mosquito.

Galizi R, Doyle LA, Menichelli M, Bernardini F, Deredec A, Burt A, Stoddard BL, Windbichler N, Crisanti A. Galizi R, et al. Among authors: doyle la. Nat Commun. 2014 Jun 10;5:3977. doi: 10.1038/ncomms4977. Nat Commun. 2014. PMID: 24915045 Free PMC article.

6

Precise assembly of complex beta sheet topologies from de novo designed building blocks.

King IC, Gleixner J, Doyle L, Kuzin A, Hunt JF, Xiao R, Montelione GT, Stoddard BL, DiMaio F, Baker D. King IC, et al. Among authors: doyle l. Elife. 2015 Dec 9;4:e11012. doi: 10.7554/eLife.11012. Elife. 2015. PMID: 26650357 Free PMC article.

7

Rational design of α-helical tandem repeat proteins with closed architectures.

Doyle L, Hallinan J, Bolduc J, Parmeggiani F, Baker D, Stoddard BL, Bradley P. Doyle L, et al. Nature. 2015 Dec 24;528(7583):585-8. doi: 10.1038/nature16191. Epub 2015 Dec 16. Nature. 2015. PMID: 26675735 Free PMC article.

8

The effect of increasing numbers of repeats on TAL effector DNA binding specificity.

Rinaldi FC, Doyle LA, Stoddard BL, Bogdanove AJ. Rinaldi FC, et al. Among authors: doyle la. Nucleic Acids Res. 2017 Jun 20;45(11):6960-6970. doi: 10.1093/nar/gkx342. Nucleic Acids Res. 2017. PMID: 28460076 Free PMC article.

9

Sampling and energy evaluation challenges in ligand binding protein design.

Dou J, Doyle L, Jr Greisen P, Schena A, Park H, Johnsson K, Stoddard BL, Baker D. Dou J, et al. Among authors: doyle l. Protein Sci. 2017 Dec;26(12):2426-2437. doi: 10.1002/pro.3317. Epub 2017 Oct 30. Protein Sci. 2017. PMID: 28980354 Free PMC article.

10

De novo design of a fluorescence-activating β-barrel.

Dou J, Vorobieva AA, Sheffler W, Doyle LA, Park H, Bick MJ, Mao B, Foight GW, Lee MY, Gagnon LA, Carter L, Sankaran B, Ovchinnikov S, Marcos E, Huang PS, Vaughan JC, Stoddard BL, Baker D. Dou J, et al. Among authors: doyle la. Nature. 2018 Sep;561(7724):485-491. doi: 10.1038/s41586-018-0509-0. Epub 2018 Sep 12. Nature. 2018. PMID: 30209393 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,355 results

Search Page

Filters