Leng Y - Search Results

1

Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation.

Marinova Z, Ren M, Wendland JR, Leng Y, Liang MH, Yasuda S, Leeds P, Chuang DM. Marinova Z, et al. Among authors: leng y. J Neurochem. 2009 Nov;111(4):976-87. doi: 10.1111/j.1471-4159.2009.06385.x. Epub 2009 Sep 18. J Neurochem. 2009. PMID: 19765194 Free PMC article.

2

Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction.

Ren M, Leng Y, Jeong M, Leeds PR, Chuang DM. Ren M, et al. Among authors: leng y. J Neurochem. 2004 Jun;89(6):1358-67. doi: 10.1111/j.1471-4159.2004.02406.x. J Neurochem. 2004. PMID: 15189338 Free article.

3

Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity.

Leng Y, Chuang DM. Leng Y, et al. J Neurosci. 2006 Jul 12;26(28):7502-12. doi: 10.1523/JNEUROSCI.0096-06.2006. J Neurosci. 2006. PMID: 16837598 Free PMC article.

4

Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition.

Leng Y, Liang MH, Ren M, Marinova Z, Leeds P, Chuang DM. Leng Y, et al. J Neurosci. 2008 Mar 5;28(10):2576-88. doi: 10.1523/JNEUROSCI.5467-07.2008. J Neurosci. 2008. PMID: 18322101 Free PMC article.

5

Potent neuroprotective effects of novel structural derivatives of valproic acid: potential roles of HDAC inhibition and HSP70 induction.

Leng Y, Marinova Z, Reis-Fernandes MA, Nau H, Chuang DM. Leng Y, et al. Neurosci Lett. 2010 Jun 7;476(3):127-32. doi: 10.1016/j.neulet.2010.04.013. Epub 2010 Apr 13. Neurosci Lett. 2010. PMID: 20394799 Free PMC article.

6

The mood stabilizers valproic acid and lithium enhance mesenchymal stem cell migration via distinct mechanisms.

Tsai LK, Leng Y, Wang Z, Leeds P, Chuang DM. Tsai LK, et al. Among authors: leng y. Neuropsychopharmacology. 2010 Oct;35(11):2225-37. doi: 10.1038/npp.2010.97. Epub 2010 Jul 7. Neuropsychopharmacology. 2010. PMID: 20613717 Free PMC article.

7

Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons.

Marinova Z, Leng Y, Leeds P, Chuang DM. Marinova Z, et al. Among authors: leng y. Neuropharmacology. 2011 Jun;60(7-8):1109-15. doi: 10.1016/j.neuropharm.2010.09.022. Epub 2010 Oct 1. Neuropharmacology. 2011. PMID: 20888352 Free PMC article.

8

Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition.

Wang Z, Leng Y, Tsai LK, Leeds P, Chuang DM. Wang Z, et al. Among authors: leng y. J Cereb Blood Flow Metab. 2011 Jan;31(1):52-7. doi: 10.1038/jcbfm.2010.195. Epub 2010 Oct 27. J Cereb Blood Flow Metab. 2011. PMID: 20978517 Free PMC article.

9

Valproic Acid and Other HDAC Inhibitors Upregulate FGF21 Gene Expression and Promote Process Elongation in Glia by Inhibiting HDAC2 and 3.

Leng Y, Wang J, Wang Z, Liao HM, Wei M, Leeds P, Chuang DM. Leng Y, et al. Int J Neuropsychopharmacol. 2016 Aug 12;19(8):pyw035. doi: 10.1093/ijnp/pyw035. Print 2016 Aug. Int J Neuropsychopharmacol. 2016. PMID: 27207921 Free PMC article.

10

Neuronal apoptosis induced by pharmacological concentrations of 3-hydroxykynurenine: characterization and protection by dantrolene and Bcl-2 overexpression.

Wei H, Leeds P, Chen RW, Wei W, Leng Y, Bredesen DE, Chuang DM. Wei H, et al. Among authors: leng y. J Neurochem. 2000 Jul;75(1):81-90. doi: 10.1046/j.1471-4159.2000.0750081.x. J Neurochem. 2000. PMID: 10854250 Free article.

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