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Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop.
Pfuhler S, Kirkland D, Kasper P, Hayashi M, Vanparys P, Carmichael P, Dertinger S, Eastmond D, Elhajouji A, Krul C, Rothfuss A, Schoening G, Smith A, Speit G, Thomas C, van Benthem J, Corvi R. Pfuhler S, et al. Among authors: rothfuss a. Mutat Res. 2009 Nov-Dec;680(1-2):31-42. doi: 10.1016/j.mrgentox.2009.09.002. Epub 2009 Sep 16. Mutat Res. 2009. PMID: 19765670
Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.
Rothfuss A, Honma M, Czich A, Aardema MJ, Burlinson B, Galloway S, Hamada S, Kirkland D, Heflich RH, Howe J, Nakajima M, O'Donovan M, Plappert-Helbig U, Priestley C, Recio L, Schuler M, Uno Y, Martus HJ. Rothfuss A, et al. Mutat Res. 2011 Aug 16;723(2):108-20. doi: 10.1016/j.mrgentox.2010.12.005. Epub 2010 Dec 21. Mutat Res. 2011. PMID: 21182982
Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.
Rothfuss A, O'Donovan M, De Boeck M, Brault D, Czich A, Custer L, Hamada S, Plappert-Helbig U, Hayashi M, Howe J, Kraynak AR, van der Leede BJ, Nakajima M, Priestley C, Thybaud V, Saigo K, Sawant S, Shi J, Storer R, Struwe M, Vock E, Galloway S. Rothfuss A, et al. Mutat Res. 2010 Sep 30;702(1):40-69. doi: 10.1016/j.mrgentox.2010.07.006. Epub 2010 Jul 23. Mutat Res. 2010. PMID: 20656055
Genotoxicity of hyperbaric oxygen.
Speit G, Dennog C, Radermacher P, Rothfuss A. Speit G, et al. Among authors: rothfuss a. Mutat Res. 2002 Dec;512(2-3):111-9. doi: 10.1016/s1383-5742(02)00045-5. Mutat Res. 2002. PMID: 12464346 Review.
40 results