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Active site remodeling switches HIV specificity of antiretroviral TRIMCyp.
Price AJ, Marzetta F, Lammers M, Ylinen LM, Schaller T, Wilson SJ, Towers GJ, James LC. Price AJ, et al. Among authors: ylinen lm. Nat Struct Mol Biol. 2009 Oct;16(10):1036-42. doi: 10.1038/nsmb.1667. Epub 2009 Sep 20. Nat Struct Mol Biol. 2009. PMID: 19767750 Free PMC article.
Independent evolution of an antiviral TRIMCyp in rhesus macaques.
Wilson SJ, Webb BL, Ylinen LM, Verschoor E, Heeney JL, Towers GJ. Wilson SJ, et al. Among authors: ylinen lm. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3557-62. doi: 10.1073/pnas.0709003105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287035 Free PMC article.
Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core structure.
Eickholt BJ, Towers GJ, Ryves WJ, Eikel D, Adley K, Ylinen LM, Chadborn NH, Harwood AJ, Nau H, Williams RS. Eickholt BJ, et al. Among authors: ylinen lm. Mol Pharmacol. 2005 May;67(5):1426-33. doi: 10.1124/mol.104.009308. Epub 2005 Feb 1. Mol Pharmacol. 2005. PMID: 15687223 Free PMC article.
14 results