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A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia.
Ivanciu L, Toso R, Margaritis P, Pavani G, Kim H, Schlachterman A, Liu JH, Clerin V, Pittman DD, Rose-Miranda R, Shields KM, Erbe DV, Tobin JF, Arruda VR, Camire RM. Ivanciu L, et al. Among authors: toso r. Nat Biotechnol. 2011 Oct 23;29(11):1028-33. doi: 10.1038/nbt.1995. Nat Biotechnol. 2011. PMID: 22020385 Free PMC article.
Factor V Leiden improves in vivo hemostasis in murine hemophilia models.
Schlachterman A, Schuettrumpf J, Liu JH, Furlan Freguia C, Toso R, Poncz M, Camire RM, Arruda VR. Schlachterman A, et al. Among authors: toso r. J Thromb Haemost. 2005 Dec;3(12):2730-7. doi: 10.1111/j.1538-7836.2005.01639.x. J Thromb Haemost. 2005. PMID: 16359510 Free article.
Preclinical assessment of an optimized AAV-FVIII vector in mice and non-human primates for the treatment of hemophilia A.
Elkouby L, Armour SM, Toso R, DiPietro M, Davidson RJ, Nguyen GN, Willet M, Kutza S, Silverberg J, Frick J, Crosariol M, Wang Y, Wang C, High KA, Sabatino DE, Anguela XM. Elkouby L, et al. Among authors: toso r. Mol Ther Methods Clin Dev. 2021 Nov 24;24:20-29. doi: 10.1016/j.omtm.2021.11.005. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2021. PMID: 34977269 Free PMC article.
37 results