Nitsch RM - Search Results

1

Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway.

Goodger ZV, Rajendran L, Trutzel A, Kohli BM, Nitsch RM, Konietzko U. Goodger ZV, et al. Among authors: nitsch rm. J Cell Sci. 2009 Oct 15;122(Pt 20):3703-14. doi: 10.1242/jcs.048090. Epub 2009 Sep 22. J Cell Sci. 2009. PMID: 19773363 Free article.

2

The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor.

von Rotz RC, Kohli BM, Bosset J, Meier M, Suzuki T, Nitsch RM, Konietzko U. von Rotz RC, et al. Among authors: nitsch rm. J Cell Sci. 2004 Sep 1;117(Pt 19):4435-48. doi: 10.1242/jcs.01323. J Cell Sci. 2004. PMID: 15331662 Free article.

3

Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories.

Konietzko U, Goodger ZV, Meyer M, Kohli BM, Bosset J, Lahiri DK, Nitsch RM. Konietzko U, et al. Among authors: nitsch rm. Neurobiol Aging. 2010 Jan;31(1):58-73. doi: 10.1016/j.neurobiolaging.2008.03.001. Epub 2008 Apr 10. Neurobiol Aging. 2010. PMID: 18403052 Free PMC article.

4

Turnover of amyloid precursor protein family members determines their nuclear signaling capability.

Gersbacher MT, Goodger ZV, Trutzel A, Bundschuh D, Nitsch RM, Konietzko U. Gersbacher MT, et al. Among authors: nitsch rm. PLoS One. 2013 Jul 18;8(7):e69363. doi: 10.1371/journal.pone.0069363. Print 2013. PLoS One. 2013. PMID: 23874953 Free PMC article.

5

Visualization and quantification of APP intracellular domain-mediated nuclear signaling by bimolecular fluorescence complementation.

Riese F, Grinschgl S, Gersbacher MT, Russi N, Hock C, Nitsch RM, Konietzko U. Riese F, et al. Among authors: nitsch rm. PLoS One. 2013 Sep 25;8(9):e76094. doi: 10.1371/journal.pone.0076094. eCollection 2013. PLoS One. 2013. PMID: 24086696 Free PMC article.

6

Fe65 is the sole member of its family that mediates transcription regulated by the amyloid precursor protein.

Probst S, Krüger M, Kägi L, Thöni S, Schuppli D, Nitsch RM, Konietzko U. Probst S, et al. Among authors: nitsch rm. J Cell Sci. 2020 Sep 8;133(17):jcs242917. doi: 10.1242/jcs.242917. J Cell Sci. 2020. PMID: 32843577 Free article.

7

Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice.

Knobloch M, Konietzko U, Krebs DC, Nitsch RM. Knobloch M, et al. Among authors: nitsch rm. Neurobiol Aging. 2007 Sep;28(9):1297-306. doi: 10.1016/j.neurobiolaging.2006.06.019. Epub 2006 Jul 31. Neurobiol Aging. 2007. PMID: 16876915

8

Abeta oligomer-mediated long-term potentiation impairment involves protein phosphatase 1-dependent mechanisms.

Knobloch M, Farinelli M, Konietzko U, Nitsch RM, Mansuy IM. Knobloch M, et al. Among authors: nitsch rm. J Neurosci. 2007 Jul 18;27(29):7648-53. doi: 10.1523/JNEUROSCI.0395-07.2007. J Neurosci. 2007. PMID: 17634359 Free PMC article.

9

Interactome of the amyloid precursor protein APP in brain reveals a protein network involved in synaptic vesicle turnover and a close association with Synaptotagmin-1.

Kohli BM, Pflieger D, Mueller LN, Carbonetti G, Aebersold R, Nitsch RM, Konietzko U. Kohli BM, et al. Among authors: nitsch rm. J Proteome Res. 2012 Aug 3;11(8):4075-90. doi: 10.1021/pr300123g. Epub 2012 Jul 19. J Proteome Res. 2012. PMID: 22731840

10

A fluorescent protein-readout for transcriptional activity reveals regulation of APP nuclear signaling by phosphorylation sites.

Konietzko U, Gersbacher MT, Streuli J, Krüger M, Thöni S, Kins S, Nitsch RM. Konietzko U, et al. Among authors: nitsch rm. Biol Chem. 2019 Aug 27;400(9):1191-1203. doi: 10.1515/hsz-2019-0125. Biol Chem. 2019. PMID: 31120852 Free article.

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