Ketola K - Search Results

1

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth.

Iljin K, Ketola K, Vainio P, Halonen P, Kohonen P, Fey V, Grafström RC, Perälä M, Kallioniemi O. Iljin K, et al. Among authors: ketola k. Clin Cancer Res. 2009 Oct 1;15(19):6070-8. doi: 10.1158/1078-0432.CCR-09-1035. Epub 2009 Sep 29. Clin Cancer Res. 2009. PMID: 19789329

2

PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma.

Puustinen P, Junttila MR, Vanhatupa S, Sablina AA, Hector ME, Teittinen K, Raheem O, Ketola K, Lin S, Kast J, Haapasalo H, Hahn WC, Westermarck J. Puustinen P, et al. Among authors: ketola k. Cancer Res. 2009 Apr 1;69(7):2870-7. doi: 10.1158/0008-5472.CAN-08-2760. Epub 2009 Mar 17. Cancer Res. 2009. PMID: 19293187 Free PMC article.

3

Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells.

Ketola K, Vainio P, Fey V, Kallioniemi O, Iljin K. Ketola K, et al. Mol Cancer Ther. 2010 Dec;9(12):3175-85. doi: 10.1158/1535-7163.MCT-10-0368. Mol Cancer Ther. 2010. PMID: 21159605

4

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.

Vainio P, Gupta S, Ketola K, Mirtti T, Mpindi JP, Kohonen P, Fey V, Perälä M, Smit F, Verhaegh G, Schalken J, Alanen KA, Kallioniemi O, Iljin K. Vainio P, et al. Among authors: ketola k. Am J Pathol. 2011 Feb;178(2):525-36. doi: 10.1016/j.ajpath.2010.10.002. Am J Pathol. 2011. PMID: 21281786 Free PMC article.

5

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.

Ketola K, Hilvo M, Hyötyläinen T, Vuoristo A, Ruskeepää AL, Orešič M, Kallioniemi O, Iljin K. Ketola K, et al. Br J Cancer. 2012 Jan 3;106(1):99-106. doi: 10.1038/bjc.2011.530. Br J Cancer. 2012. PMID: 22215106 Free PMC article.

6

Chemical biology drug sensitivity screen identifies sunitinib as synergistic agent with disulfiram in prostate cancer cells.

Ketola K, Kallioniemi O, Iljin K. Ketola K, et al. PLoS One. 2012;7(12):e51470. doi: 10.1371/journal.pone.0051470. Epub 2012 Dec 12. PLoS One. 2012. PMID: 23251544 Free PMC article.

7

High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion.

Lehtinen L, Ketola K, Mäkelä R, Mpindi JP, Viitala M, Kallioniemi O, Iljin K. Lehtinen L, et al. Among authors: ketola k. Oncotarget. 2013 Jan;4(1):48-63. doi: 10.18632/oncotarget.756. Oncotarget. 2013. PMID: 23295955 Free PMC article.

8

High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer.

Ketola K, Viitala M, Kohonen P, Fey V, Culig Z, Kallioniemi O, Iljin K. Ketola K, et al. J Mol Biochem. 2016 Mar 30;5(1):12-22. J Mol Biochem. 2016. PMID: 27891324 Free PMC article.

9

Targeting Prostate Cancer Subtype 1 by Forkhead Box M1 Pathway Inhibition.

Ketola K, Munuganti RSN, Davies A, Nip KM, Bishop JL, Zoubeidi A. Ketola K, et al. Clin Cancer Res. 2017 Nov 15;23(22):6923-6933. doi: 10.1158/1078-0432.CCR-17-0901. Epub 2017 Sep 12. Clin Cancer Res. 2017. PMID: 28899970

10

Subclone Eradication Analysis Identifies Targets for Enhanced Cancer Therapy and Reveals L1 Retrotransposition as a Dynamic Source of Cancer Heterogeneity.

Ketola K, Kaljunen H, Taavitsainen S, Kaarijärvi R, Järvelä E, Rodríguez-Martín B, Haase K, Woodcock DJ, Tubio J, Wedge DC, Nykter M, Bova GS. Ketola K, et al. Cancer Res. 2021 Oct 1;81(19):4901-4909. doi: 10.1158/0008-5472.CAN-21-0371. Epub 2021 Sep 8. Cancer Res. 2021. PMID: 34348967 Free PMC article.

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