Verbrugge I - Search Results

1

Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation.

Verbrugge I, Maas C, Heijkoop M, Verheij M, Borst J. Verbrugge I, et al. Cell Death Differ. 2010 Mar;17(3):551-61. doi: 10.1038/cdd.2009.141. Epub 2009 Oct 2. Cell Death Differ. 2010. PMID: 19798106

2

Ionizing radiation modulates the TRAIL death-inducing signaling complex, allowing bypass of the mitochondrial apoptosis pathway.

Verbrugge I, de Vries E, Tait SW, Wissink EH, Walczak H, Verheij M, Borst J. Verbrugge I, et al. Oncogene. 2008 Jan 24;27(5):574-84. doi: 10.1038/sj.onc.1210696. Epub 2007 Aug 6. Oncogene. 2008. PMID: 17684487

3

Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation.

Maas C, Verbrugge I, de Vries E, Savich G, van de Kooij LW, Tait SW, Borst J. Maas C, et al. Among authors: verbrugge i. Cell Death Differ. 2010 Oct;17(10):1613-23. doi: 10.1038/cdd.2010.39. Epub 2010 Apr 16. Cell Death Differ. 2010. PMID: 20395960

4

TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy.

Wissink EH, Verbrugge I, Vink SR, Schader MB, Schaefer U, Walczak H, Borst J, Verheij M. Wissink EH, et al. Among authors: verbrugge i. Radiother Oncol. 2006 Aug;80(2):214-22. doi: 10.1016/j.radonc.2006.07.030. Epub 2006 Aug 17. Radiother Oncol. 2006. PMID: 16916556

5

Combining radiotherapy with APO010 in cancer treatment.

Verbrugge I, Wissink EH, Rooswinkel RW, Jongsma J, Beltraminelli N, Dupuis M, Borst J, Verheij M. Verbrugge I, et al. Clin Cancer Res. 2009 Mar 15;15(6):2031-8. doi: 10.1158/1078-0432.CCR-08-2125. Epub 2009 Mar 10. Clin Cancer Res. 2009. PMID: 19276268

6

Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1.

van de Kooij B, Verbrugge I, de Vries E, Gijsen M, Montserrat V, Maas C, Neefjes J, Borst J. van de Kooij B, et al. Among authors: verbrugge i. J Biol Chem. 2013 Mar 1;288(9):6617-28. doi: 10.1074/jbc.M112.448209. Epub 2013 Jan 8. J Biol Chem. 2013. PMID: 23300075 Free PMC article.

7

The curative outcome of radioimmunotherapy in a mouse breast cancer model relies on mTOR signaling.

Verbrugge I, Gasparini A, Haynes NM, Hagekyriakou J, Galli M, Stewart TJ, Abrams SI, Yagita H, Verheij M, Johnstone RW, Borst J, Neefjes J. Verbrugge I, et al. Radiat Res. 2014 Aug;182(2):219-29. doi: 10.1667/RR13511.1. Epub 2014 Jun 24. Radiat Res. 2014. PMID: 24960417

8

Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma.

Kroon P, Gadiot J, Peeters M, Gasparini A, Deken MA, Yagita H, Verheij M, Borst J, Blank CU, Verbrugge I. Kroon P, et al. Among authors: verbrugge i. Cancer Immunol Immunother. 2016 Jun;65(6):753-63. doi: 10.1007/s00262-016-1843-4. Epub 2016 May 9. Cancer Immunol Immunother. 2016. PMID: 27160390 Free PMC article.

9

Radiotherapy and Cisplatin Increase Immunotherapy Efficacy by Enabling Local and Systemic Intratumoral T-cell Activity.

Kroon P, Frijlink E, Iglesias-Guimarais V, Volkov A, van Buuren MM, Schumacher TN, Verheij M, Borst J, Verbrugge I. Kroon P, et al. Among authors: verbrugge i. Cancer Immunol Res. 2019 Apr;7(4):670-682. doi: 10.1158/2326-6066.CIR-18-0654. Epub 2019 Feb 19. Cancer Immunol Res. 2019. PMID: 30782666

10

Enhancing radiation response by a second-generation TRAIL receptor agonist using a new in vitro organoid model system.

Zerp SF, Bibi Z, Verbrugge I, Voest EE, Verheij M. Zerp SF, et al. Among authors: verbrugge i. Clin Transl Radiat Oncol. 2020 Jun 9;24:1-9. doi: 10.1016/j.ctro.2020.05.012. eCollection 2020 Sep. Clin Transl Radiat Oncol. 2020. PMID: 32577539 Free PMC article.

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