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Page 1
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease.
Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Díaz-Hernández M, Ruiz C, Sendtner M, Lucas JJ, de Yébenes JG, Marsicano G, Monory K, Lutz B, Romero J, Alberch J, Ginés S, Kraus J, Fernández-Ruiz J, Galve-Roperh I, Guzmán M. Blázquez C, et al. Among authors: resel e. Brain. 2011 Jan;134(Pt 1):119-36. doi: 10.1093/brain/awq278. Epub 2010 Oct 7. Brain. 2011. PMID: 20929960
A restricted population of CB1 cannabinoid receptors with neuroprotective activity.
Chiarlone A, Bellocchio L, Blázquez C, Resel E, Soria-Gómez E, Cannich A, Ferrero JJ, Sagredo O, Benito C, Romero J, Sánchez-Prieto J, Lutz B, Fernández-Ruiz J, Galve-Roperh I, Guzmán M. Chiarlone A, et al. Among authors: resel e. Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8257-62. doi: 10.1073/pnas.1400988111. Epub 2014 May 19. Proc Natl Acad Sci U S A. 2014. PMID: 24843137 Free PMC article.
A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington's disease.
López-Sendón Moreno JL, García Caldentey J, Trigo Cubillo P, Ruiz Romero C, García Ribas G, Alonso Arias MA, García de Yébenes MJ, Tolón RM, Galve-Roperh I, Sagredo O, Valdeolivas S, Resel E, Ortega-Gutierrez S, García-Bermejo ML, Fernández Ruiz J, Guzmán M, García de Yébenes Prous J. López-Sendón Moreno JL, et al. Among authors: resel e. J Neurol. 2016 Jul;263(7):1390-400. doi: 10.1007/s00415-016-8145-9. Epub 2016 May 9. J Neurol. 2016. PMID: 27159993 Clinical Trial.
Astroglial monoacylglycerol lipase controls mutant huntingtin-induced damage of striatal neurons.
Ruiz-Calvo A, Bajo-Grañeras R, Maroto IB, Zian D, Grabner GF, García-Taboada E, Resel E, Zechner R, Zimmermann R, Ortega-Gutiérrez S, Galve-Roperh I, Bellocchio L, Guzmán M. Ruiz-Calvo A, et al. Among authors: resel e. Neuropharmacology. 2019 May 15;150:134-144. doi: 10.1016/j.neuropharm.2019.03.027. Epub 2019 Mar 23. Neuropharmacology. 2019. PMID: 30914306
Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum.
Moreno E, Chiarlone A, Medrano M, Puigdellívol M, Bibic L, Howell LA, Resel E, Puente N, Casarejos MJ, Perucho J, Botta J, Suelves N, Ciruela F, Ginés S, Galve-Roperh I, Casadó V, Grandes P, Lutz B, Monory K, Canela EI, Lluís C, McCormick PJ, Guzmán M. Moreno E, et al. Among authors: resel e. Neuropsychopharmacology. 2018 Apr;43(5):964-977. doi: 10.1038/npp.2017.12. Epub 2017 Jan 19. Neuropsychopharmacology. 2018. PMID: 28102227 Free PMC article.
Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination.
Blázquez C, Ruiz-Calvo A, Bajo-Grañeras R, Baufreton JM, Resel E, Varilh M, Pagano Zottola AC, Mariani Y, Cannich A, Rodríguez-Navarro JA, Marsicano G, Galve-Roperh I, Bellocchio L, Guzmán M. Blázquez C, et al. Among authors: resel e. Elife. 2020 Aug 10;9:e56811. doi: 10.7554/eLife.56811. Elife. 2020. PMID: 32773031 Free PMC article.
Δ9 -Tetrahydrocannabinol promotes functional remyelination in the mouse brain.
Aguado T, Huerga-Gómez A, Sánchez-de la Torre A, Resel E, Chara JC, Matute C, Mato S, Galve-Roperh I, Guzman M, Palazuelos J. Aguado T, et al. Among authors: resel e. Br J Pharmacol. 2021 Oct;178(20):4176-4192. doi: 10.1111/bph.15608. Epub 2021 Aug 2. Br J Pharmacol. 2021. PMID: 34216154 Free article.
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