Hu YZ - Search Results

1

[Recent advances in the study of bioreductive drugs targeted tumor hypoxia].

Liu JB, Fu L, Hu YZ, Jiang FQ. Liu JB, et al. Among authors: hu yz. Yao Xue Xue Bao. 2009 Jul;44(7):695-702. Yao Xue Xue Bao. 2009. PMID: 19806905 Review. Chinese.

2

Synthesis and hypoxic-cytotoxic activity of some 3-amino-1,2,4-benzotriazine-1,4-dioxide derivatives.

Jiang F, Yang B, Fan L, He Q, Hu Y. Jiang F, et al. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4209-13. doi: 10.1016/j.bmcl.2006.05.095. Epub 2006 Jun 13. Bioorg Med Chem Lett. 2006. PMID: 16777409

3

Synthesis, structure and hypoxic cytotoxicity of 3-amino-1,2,4-benzotriazine-1,4-dioxide derivatives.

Jiang F, Weng Q, Sheng R, Xia Q, He Q, Yang B, Hu Y. Jiang F, et al. Arch Pharm (Weinheim). 2007 May;340(5):258-63. doi: 10.1002/ardp.200600201. Arch Pharm (Weinheim). 2007. PMID: 17464965

4

Synthesis, hypoxia-selective cytotoxicity of new 3-amino-1,2,4-benzotriazine-1,4-dioxide derivatives.

Xia Q, Zhang L, Zhang J, Sheng R, Yang B, He Q, Hu Y. Xia Q, et al. Eur J Med Chem. 2011 Mar;46(3):919-26. doi: 10.1016/j.ejmech.2011.01.007. Epub 2011 Jan 15. Eur J Med Chem. 2011. PMID: 21281992

5

Hypoxia-Targeted Drug Q6 Induces G2-M Arrest and Apoptosis via Poisoning Topoisomerase II under Hypoxia.

Chang L, Liu X, Wang D, Ma J, Zhou T, Chen Y, Sheng R, Hu Y, Du Y, He Q, Yang B, Zhu H. Chang L, et al. PLoS One. 2015 Dec 9;10(12):e0144506. doi: 10.1371/journal.pone.0144506. eCollection 2015. PLoS One. 2015. PMID: 26649750 Free PMC article.

6

PI3K inhibitors for cancer therapy: what has been achieved so far?

Wu P, Liu T, Hu Y. Wu P, et al. Curr Med Chem. 2009;16(8):916-30. doi: 10.2174/092986709787581905. Curr Med Chem. 2009. PMID: 19275602

7

Recent advances in the development of small-molecule CCR5 inhibitors for HIV.

Liu T, Weng Z, Dong X, Hu Y. Liu T, et al. Mini Rev Med Chem. 2010 Nov;10(13):1277-92. doi: 10.2174/13895575110091277. Mini Rev Med Chem. 2010. PMID: 20854256 Review.

8

Q39, a novel synthetic Quinoxaline 1,4-Di-N-oxide compound with anti-cancer activity in hypoxia.

Weng Q, Wang D, Guo P, Fang L, Hu Y, He Q, Yang B. Weng Q, et al. Eur J Pharmacol. 2008 Mar 10;581(3):262-9. doi: 10.1016/j.ejphar.2007.12.006. Epub 2007 Dec 15. Eur J Pharmacol. 2008. PMID: 18215659

9

Synthesis and biological evaluation of 3-aryl-quinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives as hypoxic selective anti-tumor agents.

Hu Y, Xia Q, Shangguan S, Liu X, Hu Y, Sheng R. Hu Y, et al. Molecules. 2012 Aug 13;17(8):9683-96. doi: 10.3390/molecules17089683. Molecules. 2012. PMID: 22890172 Free PMC article.

10

Furthering the design and the discovery of small molecule ATP-competitive mTOR inhibitors as an effective cancer treatment.

Lv X, Ma X, Hu Y. Lv X, et al. Expert Opin Drug Discov. 2013 Aug;8(8):991-1012. doi: 10.1517/17460441.2013.800479. Epub 2013 May 14. Expert Opin Drug Discov. 2013. PMID: 23668243 Review.

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