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Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium; Todd JA, Wallace C, Concannon P, Rich SS. Onengut-Gumuscu S, et al. Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9. Nat Genet. 2015. PMID: 25751624 Free PMC article.
Prediction and prevention of Type 1 diabetes mellitus.
Zhang L, Eisenbarth GS. Zhang L, et al. Among authors: eisenbarth gs. J Diabetes. 2011 Mar;3(1):48-57. doi: 10.1111/j.1753-0407.2010.00102.x. J Diabetes. 2011. PMID: 21073664 Free article. Review.
Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry.
Hunt KA, Smyth DJ, Balschun T, Ban M, Mistry V, Ahmad T, Anand V, Barrett JC, Bhaw-Rosun L, Bockett NA, Brand OJ, Brouwer E, Concannon P, Cooper JD, Dias KR, van Diemen CC, Dubois PC, Edkins S, Fölster-Holst R, Fransen K, Glass DN, Heap GA, Hofmann S, Huizinga TW, Hunt S, Langford C, Lee J, Mansfield J, Marrosu MG, Mathew CG, Mein CA, Müller-Quernheim J, Nutland S, Onengut-Gumuscu S, Ouwehand W, Pearce K, Prescott NJ, Posthumus MD, Potter S, Rosati G, Sambrook J, Satsangi J, Schreiber S, Shtir C, Simmonds MJ, Sudman M, Thompson SD, Toes R, Trynka G, Vyse TJ, Walker NM, Weidinger S, Zhernakova A, Zoledziewska M; Type 1 Diabetes Genetics Consortium; UK Inflammatory Bowel Disease (IBD) Genetics Consortium; Wellcome Trust Case Control Consortium; Weersma RK, Gough SC, Sawcer S, Wijmenga C, Parkes M, Cucca F, Franke A, Deloukas P, Rich SS, Todd JA, van Heel DA. Hunt KA, et al. Nat Genet. 2011 Dec 27;44(1):3-5. doi: 10.1038/ng.1037. Nat Genet. 2011. PMID: 22200769 Free PMC article. No abstract available.
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; Type 1 Diabetes Genetics Consortium. Barrett JC, et al. Nat Genet. 2009 Jun;41(6):703-7. doi: 10.1038/ng.381. Epub 2009 May 10. Nat Genet. 2009. PMID: 19430480 Free PMC article.
Insulin as an autoantigen in NOD/human diabetes.
Zhang L, Nakayama M, Eisenbarth GS. Zhang L, et al. Among authors: eisenbarth gs. Curr Opin Immunol. 2008 Feb;20(1):111-8. doi: 10.1016/j.coi.2007.11.005. Curr Opin Immunol. 2008. PMID: 18178393 Free PMC article. Review.
Conserved T cell receptor alpha-chain induces insulin autoantibodies.
Kobayashi M, Jasinski J, Liu E, Li M, Miao D, Zhang L, Yu L, Nakayama M, Eisenbarth GS. Kobayashi M, et al. Among authors: eisenbarth gs. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10090-4. doi: 10.1073/pnas.0801648105. Epub 2008 Jul 14. Proc Natl Acad Sci U S A. 2008. PMID: 18626021 Free PMC article.
Type 1 diabetes: chronic progressive autoimmune disease.
Zhang L, Gianani R, Nakayama M, Liu E, Kobayashi M, Baschal E, Yu L, Babu S, Dawson A, Johnson K, Jahromi M, Aly T, Fain P, Barker J, Rewers M, Eisenbarth GS. Zhang L, et al. Among authors: eisenbarth gs. Novartis Found Symp. 2008;292:85-94; discussion 94-8, 122-9, 202-3. doi: 10.1002/9780470697405.ch7. Novartis Found Symp. 2008. PMID: 19203094
480 results