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Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA.
Vispé S, DeVries L, Créancier L, Besse J, Bréand S, Hobson DJ, Svejstrup JQ, Annereau JP, Cussac D, Dumontet C, Guilbaud N, Barret JM, Bailly C. Vispé S, et al. Among authors: devries l. Mol Cancer Ther. 2009 Oct;8(10):2780-90. doi: 10.1158/1535-7163.MCT-09-0549. Epub 2009 Oct 6. Mol Cancer Ther. 2009. PMID: 19808979
Pharmacological evaluation of a series of smoothened antagonists in signaling pathways and after topical application in a depilated mouse model.
Lauressergues E, Heusler P, Lestienne F, Troulier D, Rauly-Lestienne I, Tourette A, Ailhaud MC, Cathala C, Tardif S, Denais-Laliève D, Calmettes MT, Degryse AD, Dumoulin A, De Vries L, Cussac D. Lauressergues E, et al. Pharmacol Res Perspect. 2016 Mar 4;4(2):e00214. doi: 10.1002/prp2.214. eCollection 2016 Apr. Pharmacol Res Perspect. 2016. PMID: 27069629 Free PMC article.
65 results