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Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA.
Vispé S, DeVries L, Créancier L, Besse J, Bréand S, Hobson DJ, Svejstrup JQ, Annereau JP, Cussac D, Dumontet C, Guilbaud N, Barret JM, Bailly C. Vispé S, et al. Among authors: svejstrup jq. Mol Cancer Ther. 2009 Oct;8(10):2780-90. doi: 10.1158/1535-7163.MCT-09-0549. Epub 2009 Oct 6. Mol Cancer Ther. 2009. PMID: 19808979
RNA polymerase II collision interrupts convergent transcription.
Hobson DJ, Wei W, Steinmetz LM, Svejstrup JQ. Hobson DJ, et al. Among authors: svejstrup jq. Mol Cell. 2012 Nov 9;48(3):365-74. doi: 10.1016/j.molcel.2012.08.027. Epub 2012 Oct 4. Mol Cell. 2012. PMID: 23041286 Free PMC article.
Direct inhibition of RNA polymerase II transcription by RECQL5.
Aygün O, Xu X, Liu Y, Takahashi H, Kong SE, Conaway RC, Conaway JW, Svejstrup JQ. Aygün O, et al. Among authors: svejstrup jq. J Biol Chem. 2009 Aug 28;284(35):23197-203. doi: 10.1074/jbc.M109.015750. Epub 2009 Jul 1. J Biol Chem. 2009. PMID: 19570979 Free PMC article.
Transcript Elongation by RNA Polymerase II.
Selth LA, Sigurdsson S, Svejstrup JQ. Selth LA, et al. Among authors: svejstrup jq. Annu Rev Biochem. 2010;79:271-93. doi: 10.1146/annurev.biochem.78.062807.091425. Annu Rev Biochem. 2010. PMID: 20367031 Review.
144 results