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Page 1
Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm.
Alhede M, Kragh KN, Qvortrup K, Allesen-Holm M, van Gennip M, Christensen LD, Jensen PØ, Nielsen AK, Parsek M, Wozniak D, Molin S, Tolker-Nielsen T, Høiby N, Givskov M, Bjarnsholt T. Alhede M, et al. Among authors: van gennip m. PLoS One. 2011;6(11):e27943. doi: 10.1371/journal.pone.0027943. Epub 2011 Nov 21. PLoS One. 2011. PMID: 22132176 Free PMC article.
Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model.
Christensen LD, van Gennip M, Jakobsen TH, Alhede M, Hougen HP, Høiby N, Bjarnsholt T, Givskov M. Christensen LD, et al. Among authors: van gennip m. J Antimicrob Chemother. 2012 May;67(5):1198-206. doi: 10.1093/jac/dks002. Epub 2012 Feb 1. J Antimicrob Chemother. 2012. PMID: 22302561
Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing.
Jakobsen TH, van Gennip M, Phipps RK, Shanmugham MS, Christensen LD, Alhede M, Skindersoe ME, Rasmussen TB, Friedrich K, Uthe F, Jensen PØ, Moser C, Nielsen KF, Eberl L, Larsen TO, Tanner D, Høiby N, Bjarnsholt T, Givskov M. Jakobsen TH, et al. Among authors: van gennip m. Antimicrob Agents Chemother. 2012 May;56(5):2314-25. doi: 10.1128/AAC.05919-11. Epub 2012 Feb 6. Antimicrob Agents Chemother. 2012. PMID: 22314537 Free PMC article.
Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection.
Calum H, Moser C, Jensen PØ, Christophersen L, Maling DS, van Gennip M, Bjarnsholt T, Hougen HP, Givskov M, Jacobsen GK, Høiby N. Calum H, et al. Among authors: van gennip m. Clin Exp Immunol. 2009 Apr;156(1):102-10. doi: 10.1111/j.1365-2249.2008.03861.x. Epub 2008 Dec 11. Clin Exp Immunol. 2009. PMID: 19210518 Free PMC article.
Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes.
Van Gennip M, Christensen LD, Alhede M, Phipps R, Jensen PØ, Christophersen L, Pamp SJ, Moser C, Mikkelsen PJ, Koh AY, Tolker-Nielsen T, Pier GB, Høiby N, Givskov M, Bjarnsholt T. Van Gennip M, et al. APMIS. 2009 Jul;117(7):537-46. doi: 10.1111/j.1600-0463.2009.02466.x. APMIS. 2009. PMID: 19594494 Free PMC article.
Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes.
Alhede M, Bjarnsholt T, Jensen PØ, Phipps RK, Moser C, Christophersen L, Christensen LD, van Gennip M, Parsek M, Høiby N, Rasmussen TB, Givskov M. Alhede M, et al. Among authors: van gennip m. Microbiology (Reading). 2009 Nov;155(Pt 11):3500-3508. doi: 10.1099/mic.0.031443-0. Epub 2009 Jul 30. Microbiology (Reading). 2009. PMID: 19643762 Free article.
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