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Homozygosity of the polymorphism MICA5.1 identifies extreme risk of progression to overt adrenal insufficiency among 21-hydroxylase antibody-positive patients with type 1 diabetes.
Triolo TM, Baschal EE, Armstrong TK, Toews CS, Fain PR, Rewers MJ, Yu L, Miao D, Eisenbarth GS, Gottlieb PA, Barker JM. Triolo TM, et al. Among authors: baschal ee. J Clin Endocrinol Metab. 2009 Nov;94(11):4517-23. doi: 10.1210/jc.2009-1308. Epub 2009 Oct 9. J Clin Endocrinol Metab. 2009. PMID: 19820007 Free PMC article.
Type 1 diabetes: chronic progressive autoimmune disease.
Zhang L, Gianani R, Nakayama M, Liu E, Kobayashi M, Baschal E, Yu L, Babu S, Dawson A, Johnson K, Jahromi M, Aly T, Fain P, Barker J, Rewers M, Eisenbarth GS. Zhang L, et al. Novartis Found Symp. 2008;292:85-94; discussion 94-8, 122-9, 202-3. doi: 10.1002/9780470697405.ch7. Novartis Found Symp. 2008. PMID: 19203094
rs2476601 T allele (R620W) defines high-risk PTPN22 type I diabetes-associated haplotypes with preliminary evidence for an additional protective haplotype.
Steck AK, Baschal EE, Jasinski JM, Boehm BO, Bottini N, Concannon P, Julier C, Morahan G, Noble JA, Polychronakos C, She JX, Eisenbarth GS; Type I Diabetes Genetics Consortium. Steck AK, et al. Among authors: baschal ee. Genes Immun. 2009 Dec;10 Suppl 1(Suppl 1):S21-6. doi: 10.1038/gene.2009.87. Genes Immun. 2009. PMID: 19956096 Free PMC article.
Haplotype analysis discriminates genetic risk for DR3-associated endocrine autoimmunity and helps define extreme risk for Addison's disease.
Baker PR, Baschal EE, Fain PR, Triolo TM, Nanduri P, Siebert JC, Armstrong TK, Babu SR, Rewers MJ, Gottlieb PA, Barker JM, Eisenbarth GS. Baker PR, et al. Among authors: baschal ee. J Clin Endocrinol Metab. 2010 Oct;95(10):E263-70. doi: 10.1210/jc.2010-0508. Epub 2010 Jul 14. J Clin Endocrinol Metab. 2010. PMID: 20631027 Free PMC article.
31 results