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Simultaneous determination of ABT-888, a poly (ADP-ribose) polymerase inhibitor, and its metabolite in human plasma by liquid chromatography/tandem mass spectrometry.
Wiegand R, Wu J, Sha X, LoRusso P, Li J. Wiegand R, et al. Among authors: lorusso p. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Feb 1;878(3-4):333-9. doi: 10.1016/j.jchromb.2009.11.037. Epub 2009 Nov 27. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 20005184 Free PMC article. Clinical Trial.
Reducing undesirable hepatic clearance of a tumor-targeted vinca alkaloid via novel saccharopeptidic modifications.
Leamon CP, Reddy JA, Klein PJ, Vlahov IR, Dorton R, Bloomfield A, Nelson M, Westrick E, Parker N, Bruna K, Vetzel M, Gehrke M, Nicoson JS, Messmann RA, LoRusso PM, Sausville EA. Leamon CP, et al. Among authors: lorusso pm. J Pharmacol Exp Ther. 2011 Feb;336(2):336-43. doi: 10.1124/jpet.110.175109. Epub 2010 Oct 26. J Pharmacol Exp Ther. 2011. PMID: 20978169
A phase I study of the pharmacokinetic and safety profiles of oral pazopanib with a high-fat or low-fat meal in patients with advanced solid tumors.
Heath EI, Chiorean EG, Sweeney CJ, Hodge JP, Lager JJ, Forman K, Malburg L, Arumugham T, Dar MM, Suttle AB, Gainer SD, LoRusso P. Heath EI, et al. Among authors: lorusso p. Clin Pharmacol Ther. 2010 Dec;88(6):818-23. doi: 10.1038/clpt.2010.199. Epub 2010 Oct 27. Clin Pharmacol Ther. 2010. PMID: 20980999 Clinical Trial.
423 results