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Dengue virus capsid protein usurps lipid droplets for viral particle formation.
Samsa MM, Mondotte JA, Iglesias NG, Assunção-Miranda I, Barbosa-Lima G, Da Poian AT, Bozza PT, Gamarnik AV. Samsa MM, et al. Among authors: bozza pt. PLoS Pathog. 2009 Oct;5(10):e1000632. doi: 10.1371/journal.ppat.1000632. Epub 2009 Oct 23. PLoS Pathog. 2009. PMID: 19851456 Free PMC article.
Monocyte chemoattractant protein-1/CC chemokine ligand 2 controls microtubule-driven biogenesis and leukotriene B4-synthesizing function of macrophage lipid bodies elicited by innate immune response.
Pacheco P, Vieira-de-Abreu A, Gomes RN, Barbosa-Lima G, Wermelinger LB, Maya-Monteiro CM, Silva AR, Bozza MT, Castro-Faria-Neto HC, Bandeira-Melo C, Bozza PT. Pacheco P, et al. Among authors: bozza pt, bozza mt. J Immunol. 2007 Dec 15;179(12):8500-8. doi: 10.4049/jimmunol.179.12.8500. J Immunol. 2007. PMID: 18056397
N-(2-(arylmethylimino)ethyl)-7-chloroquinolin-4-amine derivatives, synthesized by thermal and ultrasonic means, are endowed with anti-Zika virus activity.
Barbosa-Lima G, da Silveira Pinto LS, Kaiser CR, Wardell JL, De Freitas CS, Vieira YR, Marttorelli A, Cerbino Neto J, Bozza PT, Wardell SMSV, de Souza MVN, Souza TML. Barbosa-Lima G, et al. Among authors: bozza pt. Eur J Med Chem. 2017 Feb 15;127:434-441. doi: 10.1016/j.ejmech.2017.01.007. Epub 2017 Jan 6. Eur J Med Chem. 2017. PMID: 28092859
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication.
Sacramento CQ, de Melo GR, de Freitas CS, Rocha N, Hoelz LV, Miranda M, Fintelman-Rodrigues N, Marttorelli A, Ferreira AC, Barbosa-Lima G, Abrantes JL, Vieira YR, Bastos MM, de Mello Volotão E, Nunes EP, Tschoeke DA, Leomil L, Loiola EC, Trindade P, Rehen SK, Bozza FA, Bozza PT, Boechat N, Thompson FL, de Filippis AM, Brüning K, Souza TM. Sacramento CQ, et al. Among authors: bozza pt, bozza fa. Sci Rep. 2017 Jan 18;7:40920. doi: 10.1038/srep40920. Sci Rep. 2017. PMID: 28098253 Free PMC article.
325 results