Leinwand LA - Search Results

1

Mutations at the same amino acid in myosin that cause either skeletal or cardiac myopathy have distinct molecular phenotypes.

Armel TZ, Leinwand LA. Armel TZ, et al. Among authors: leinwand la. J Mol Cell Cardiol. 2010 May;48(5):1007-13. doi: 10.1016/j.yjmcc.2009.10.011. Epub 2009 Oct 23. J Mol Cell Cardiol. 2010. PMID: 19854198 Free PMC article.

2

A 29 residue region of the sarcomeric myosin rod is necessary for filament formation.

Sohn RL, Vikstrom KL, Strauss M, Cohen C, Szent-Gyorgyi AG, Leinwand LA. Sohn RL, et al. Among authors: leinwand la. J Mol Biol. 1997 Feb 21;266(2):317-30. doi: 10.1006/jmbi.1996.0790. J Mol Biol. 1997. PMID: 9047366

3

Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy.

Roopnarine O, Leinwand LA. Roopnarine O, et al. Among authors: leinwand la. Biophys J. 1998 Dec;75(6):3023-30. doi: 10.1016/S0006-3495(98)77743-4. Biophys J. 1998. PMID: 9826622 Free PMC article.

4

Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy.

Tardiff JC, Hewett TE, Palmer BM, Olsson C, Factor SM, Moore RL, Robbins J, Leinwand LA. Tardiff JC, et al. Among authors: leinwand la. J Clin Invest. 1999 Aug;104(4):469-81. doi: 10.1172/JCI6067. J Clin Invest. 1999. PMID: 10449439 Free PMC article.

5

Animal models of hypertrophic cardiomyopathy.

Maass A, Leinwand LA. Maass A, et al. Among authors: leinwand la. Curr Opin Cardiol. 2000 May;15(3):189-96. doi: 10.1097/00001573-200005000-00012. Curr Opin Cardiol. 2000. PMID: 10952427 Review.

6

Rational promoter selection for gene transfer into cardiac cells.

Maass A, Langer SJ, Oberdorf-Maass S, Bauer S, Neyses L, Leinwand LA. Maass A, et al. Among authors: leinwand la. J Mol Cell Cardiol. 2003 Jul;35(7):823-31. doi: 10.1016/s0022-2828(03)00140-8. J Mol Cell Cardiol. 2003. PMID: 12818573

7

The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses alpha myosin heavy-chain gene expression.

Sucharov CC, Helmke SM, Langer SJ, Perryman MB, Bristow M, Leinwand L. Sucharov CC, et al. Mol Cell Biol. 2004 Oct;24(19):8705-15. doi: 10.1128/MCB.24.19.8705-8715.2004. Mol Cell Biol. 2004. PMID: 15367688 Free PMC article.

8

Yin Yang 1 represses alpha-myosin heavy chain gene expression in pathologic cardiac hypertrophy.

Mariner PD, Luckey SW, Long CS, Sucharov CC, Leinwand LA. Mariner PD, et al. Among authors: leinwand la. Biochem Biophys Res Commun. 2005 Jan 7;326(1):79-86. doi: 10.1016/j.bbrc.2004.11.008. Biochem Biophys Res Commun. 2005. PMID: 15567155

9

Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations.

Buvoli M, Hamady M, Leinwand LA, Knight R. Buvoli M, et al. Among authors: leinwand la. Trends Cardiovasc Med. 2008 May;18(4):141-9. doi: 10.1016/j.tcm.2008.04.001. Trends Cardiovasc Med. 2008. PMID: 18555187 Free PMC article. Review.

10

The role of Akt/GSK-3beta signaling in familial hypertrophic cardiomyopathy.

Luckey SW, Walker LA, Smyth T, Mansoori J, Messmer-Kratzsch A, Rosenzweig A, Olson EN, Leinwand LA. Luckey SW, et al. Among authors: leinwand la. J Mol Cell Cardiol. 2009 May;46(5):739-47. doi: 10.1016/j.yjmcc.2009.02.010. Epub 2009 Feb 21. J Mol Cell Cardiol. 2009. PMID: 19233194 Free PMC article.

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