Fujimoto T - Search Results

1

Synthesis and biological evaluation of the metabolites of 2-(1-{3-[(6-chloronaphthalen-2-yl)sulfonyl]propanoyl}piperidin-4-yl)-5-methyl-1,2-dihydro-3H-imidazo[1,5-c]imidazol-3-one.

Fujimoto T, Tobisu M, Konishi N, Kawamura M, Tada N, Takagi T, Kubo K. Fujimoto T, et al. Bioorg Med Chem. 2009 Dec 1;17(23):7993-8002. doi: 10.1016/j.bmc.2009.10.009. Epub 2009 Oct 14. Bioorg Med Chem. 2009. PMID: 19861238

2

Discovery of a tetrahydropyrimidin-2(1H)-one derivative (TAK-442) as a potent, selective, and orally active factor Xa inhibitor.

Fujimoto T, Imaeda Y, Konishi N, Hiroe K, Kawamura M, Textor GP, Aertgeerts K, Kubo K. Fujimoto T, et al. J Med Chem. 2010 May 13;53(9):3517-31. doi: 10.1021/jm901699j. J Med Chem. 2010. PMID: 20355714

3

Antithrombotic and anticoagulant profiles of TAK-442, a novel factor Xa inhibitor, in a rabbit model of venous thrombosis.

Kawamura M, Konishi N, Hiroe K, Shofuda K, Imaeda Y, Fujimoto T, Kubo K. Kawamura M, et al. Among authors: fujimoto t. J Cardiovasc Pharmacol. 2010 Aug;56(2):156-61. doi: 10.1097/FJC.0b013e3181e2bfcf. J Cardiovasc Pharmacol. 2010. PMID: 20410831

4

Lead Optimization of Influenza Virus RNA Polymerase Inhibitors Targeting PA-PB1 Interaction.

Mizuta S, Otaki H, Ishikawa T, Makau JN, Yamaguchi T, Fujimoto T, Takakura N, Sakauchi N, Kitamura S, Nono H, Nishi R, Tanaka Y, Takeda K, Nishida N, Watanabe K. Mizuta S, et al. Among authors: fujimoto t. J Med Chem. 2022 Jan 13;65(1):369-385. doi: 10.1021/acs.jmedchem.1c01527. Epub 2021 Dec 14. J Med Chem. 2022. PMID: 34905383

5

A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice.

Takagahara S, Shinohara H, Itokawa S, Satomi Y, Ando A, Yamamoto T, Suzuki H, Fujimoto T, Kubo K, Ikeda S. Takagahara S, et al. Among authors: fujimoto t. J Pharmacol Exp Ther. 2019 Nov;371(2):290-298. doi: 10.1124/jpet.119.259846. Epub 2019 Sep 5. J Pharmacol Exp Ther. 2019. PMID: 31488602

6

Impact of Fc-gamma receptor IIIA polymorphism on late-onset neutropenia and clinical outcomes in kidney transplant recipients following rituximab induction therapy.

Tashiro Y, Hyodo Y, Kitamura S, Fujimoto T, Endo T, Nishioka S, Yokoyama N, Hara T, Chiba K, Miyake H. Tashiro Y, et al. Among authors: fujimoto t. Clin Exp Nephrol. 2025 Jan 13. doi: 10.1007/s10157-024-02610-7. Online ahead of print. Clin Exp Nephrol. 2025. PMID: 39804516

7

Prognostic impact of subcutaneous fat quality and sarcopenia on the survival outcomes in patients with colorectal cancer.

Fujimoto T, Tamura K, Nagayoshi K, Mizuuchi Y, Okada Y, Osajima S, Hisano K, Horioka K, Shindo K, Ikenaga N, Nakata K, Ohuchida K, Nakamura M. Fujimoto T, et al. Surg Today. 2025 Jan 10. doi: 10.1007/s00595-024-02985-w. Online ahead of print. Surg Today. 2025. PMID: 39789347

8

Antitumor immunostimulatory effect via cell-killing action of a novel extracorporeal blood circulating photodynamic therapy system using 5-aminolevulinic acid.

Maegawa H, Kohashi M, Harada Y, Tanaka A, Kajiwara S, Fujimoto T, Atagi H, Kaneda K. Maegawa H, et al. Among authors: fujimoto t. Sci Rep. 2025 Jan 7;15(1):1064. doi: 10.1038/s41598-024-84861-8. Sci Rep. 2025. PMID: 39775122 Free PMC article.

9

Isogenic fish sperm produced by transplanting gynogenetic haploid-derived germ cells.

Nagasaka T, Fujimoto T, Saito T, Yamaha E, Arai K. Nagasaka T, et al. Among authors: fujimoto t. Biol Reprod. 2025 Jan 6:ioaf001. doi: 10.1093/biolre/ioaf001. Online ahead of print. Biol Reprod. 2025. PMID: 39761340

10

Characterization of Dystrophin Dp71 Expression and Interaction Partners in Embryonic Brain Development: Implications for Duchenne/Becker Muscular Dystrophy.

Fujimoto T, Mori M, Tonosaki M, Yaoi T, Nakano K, Okamura T, Itoh K. Fujimoto T, et al. Mol Neurobiol. 2025 Jan 6. doi: 10.1007/s12035-024-04676-6. Online ahead of print. Mol Neurobiol. 2025. PMID: 39760982

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