Besmer P - Search Results

1

Kit ligand cytoplasmic domain is essential for basolateral sorting in vivo and has roles in spermatogenesis and hematopoiesis.

Deshpande S, Agosti V, Manova K, Moore MA, Hardy MP, Besmer P. Deshpande S, et al. Among authors: besmer p. Dev Biol. 2010 Jan 15;337(2):199-210. doi: 10.1016/j.ydbio.2009.10.022. Epub 2009 Oct 27. Dev Biol. 2010. PMID: 19874813 Free PMC article.

2

Critical role for Kit-mediated Src kinase but not PI 3-kinase signaling in pro T and pro B cell development.

Agosti V, Corbacioglu S, Ehlers I, Waskow C, Sommer G, Berrozpe G, Kissel H, Tucker CM, Manova K, Moore MA, Rodewald HR, Besmer P. Agosti V, et al. Among authors: besmer p. J Exp Med. 2004 Mar 15;199(6):867-78. doi: 10.1084/jem.20031983. J Exp Med. 2004. PMID: 15024050 Free PMC article.

3

A distant upstream locus control region is critical for expression of the Kit receptor gene in mast cells.

Berrozpe G, Agosti V, Tucker C, Blanpain C, Manova K, Besmer P. Berrozpe G, et al. Among authors: besmer p. Mol Cell Biol. 2006 Aug;26(15):5850-60. doi: 10.1128/MCB.01854-05. Mol Cell Biol. 2006. PMID: 16847336 Free PMC article.

4

A role for kit receptor signaling in Leydig cell steroidogenesis.

Rothschild G, Sottas CM, Kissel H, Agosti V, Manova K, Hardy MP, Besmer P. Rothschild G, et al. Among authors: besmer p. Biol Reprod. 2003 Sep;69(3):925-32. doi: 10.1095/biolreprod.102.014548. Epub 2003 May 28. Biol Reprod. 2003. PMID: 12773427

5

The murine steel panda mutation affects kit ligand expression and growth of early ovarian follicles.

Huang EJ, Manova K, Packer AI, Sanchez S, Bachvarova RF, Besmer P. Huang EJ, et al. Among authors: besmer p. Dev Biol. 1993 May;157(1):100-9. doi: 10.1006/dbio.1993.1115. Dev Biol. 1993. PMID: 7683280 Free article.

6

Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses.

Kissel H, Timokhina I, Hardy MP, Rothschild G, Tajima Y, Soares V, Angeles M, Whitlow SR, Manova K, Besmer P. Kissel H, et al. Among authors: besmer p. EMBO J. 2000 Mar 15;19(6):1312-26. doi: 10.1093/emboj/19.6.1312. EMBO J. 2000. PMID: 10716931 Free PMC article.

7

Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.

Rossi F, Ehlers I, Agosti V, Socci ND, Viale A, Sommer G, Yozgat Y, Manova K, Antonescu CR, Besmer P. Rossi F, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12843-8. doi: 10.1073/pnas.0511076103. Epub 2006 Aug 14. Proc Natl Acad Sci U S A. 2006. PMID: 16908864 Free PMC article.

8

A KIT juxtamembrane PY567 -directed pathway provides nonredundant signals for erythroid progenitor cell development and stress erythropoiesis.

Agosti V, Karur V, Sathyanarayana P, Besmer P, Wojchowski DM. Agosti V, et al. Among authors: besmer p. Exp Hematol. 2009 Feb;37(2):159-71. doi: 10.1016/j.exphem.2008.10.009. Epub 2008 Dec 18. Exp Hematol. 2009. PMID: 19100679 Free PMC article.

9

Imatinib resistance and microcytic erythrocytosis in a KitV558Δ;T669I/+ gatekeeper-mutant mouse model of gastrointestinal stromal tumor.

Bosbach B, Deshpande S, Rossi F, Shieh JH, Sommer G, de Stanchina E, Veach DR, Scandura JM, Manova-Todorova K, Moore MA, Antonescu CR, Besmer P. Bosbach B, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):E2276-83. doi: 10.1073/pnas.1115240109. Epub 2012 May 31. Proc Natl Acad Sci U S A. 2012. PMID: 22652566 Free PMC article.

10

KIT receptor gain-of-function in hematopoiesis enhances stem cell self-renewal and promotes progenitor cell expansion.

Deshpande S, Bosbach B, Yozgat Y, Park CY, Moore MA, Besmer P. Deshpande S, et al. Among authors: besmer p. Stem Cells. 2013 Aug;31(8):1683-95. doi: 10.1002/stem.1419. Stem Cells. 2013. PMID: 23681919 Free PMC article.

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