Chien S - Search Results

1

Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway.

Lee DY, Li YS, Chang SF, Zhou J, Ho HM, Chiu JJ, Chien S. Lee DY, et al. Among authors: chien s. J Biol Chem. 2010 Jan 1;285(1):30-42. doi: 10.1074/jbc.M109.010512. Epub 2009 Nov 4. J Biol Chem. 2010. PMID: 19889638 Free PMC article.

2

The Ras-JNK pathway is involved in shear-induced gene expression.

Li YS, Shyy JY, Li S, Lee J, Su B, Karin M, Chien S. Li YS, et al. Among authors: chien s. Mol Cell Biol. 1996 Nov;16(11):5947-54. doi: 10.1128/MCB.16.11.5947. Mol Cell Biol. 1996. PMID: 8887624 Free PMC article.

3

Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases.

Li S, Kim M, Hu YL, Jalali S, Schlaepfer DD, Hunter T, Chien S, Shyy JY. Li S, et al. Among authors: chien s. J Biol Chem. 1997 Nov 28;272(48):30455-62. doi: 10.1074/jbc.272.48.30455. J Biol Chem. 1997. PMID: 9374537 Free article.

4

Shear stress activates p60src-Ras-MAPK signaling pathways in vascular endothelial cells.

Jalali S, Li YS, Sotoudeh M, Yuan S, Li S, Chien S, Shyy JY. Jalali S, et al. Among authors: chien s. Arterioscler Thromb Vasc Biol. 1998 Feb;18(2):227-34. doi: 10.1161/01.atv.18.2.227. Arterioscler Thromb Vasc Biol. 1998. PMID: 9484987

5

Effects of disturbed flow on endothelial cells.

Chiu JJ, Wang DL, Chien S, Skalak R, Usami S. Chiu JJ, et al. Among authors: chien s. J Biomech Eng. 1998 Feb;120(1):2-8. doi: 10.1115/1.2834303. J Biomech Eng. 1998. PMID: 9675673

6

Fluid shear stress activation of IkappaB kinase is integrin-dependent.

Bhullar IS, Li YS, Miao H, Zandi E, Kim M, Shyy JY, Chien S. Bhullar IS, et al. Among authors: chien s. J Biol Chem. 1998 Nov 13;273(46):30544-9. doi: 10.1074/jbc.273.46.30544. J Biol Chem. 1998. PMID: 9804824 Free article.

7

Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc.

Chen KD, Li YS, Kim M, Li S, Yuan S, Chien S, Shyy JY. Chen KD, et al. Among authors: chien s. J Biol Chem. 1999 Jun 25;274(26):18393-400. doi: 10.1074/jbc.274.26.18393. J Biol Chem. 1999. PMID: 10373445 Free article.

8

Molecular mechanism of endothelial growth arrest by laminar shear stress.

Lin K, Hsu PP, Chen BP, Yuan S, Usami S, Shyy JY, Li YS, Chien S. Lin K, et al. Among authors: chien s. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9385-9. doi: 10.1073/pnas.170282597. Proc Natl Acad Sci U S A. 2000. PMID: 10920209 Free PMC article.

9

Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands.

Jalali S, del Pozo MA, Chen K, Miao H, Li Y, Schwartz MA, Shyy JY, Chien S. Jalali S, et al. Among authors: chien s. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1042-6. doi: 10.1073/pnas.98.3.1042. Epub 2001 Jan 23. Proc Natl Acad Sci U S A. 2001. PMID: 11158591 Free PMC article.

10

Biomechanical regulation of matrix metalloproteinase-9 in cultured chondrocytes.

Jin G, Sah RL, Li YS, Lotz M, Shyy JY, Chien S. Jin G, et al. Among authors: chien s. J Orthop Res. 2000 Nov;18(6):899-908. doi: 10.1002/jor.1100180608. J Orthop Res. 2000. PMID: 11192249

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