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A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells.
Rix U, Remsing Rix LL, Terker AS, Fernbach NV, Hantschel O, Planyavsky M, Breitwieser FP, Herrmann H, Colinge J, Bennett KL, Augustin M, Till JH, Heinrich MC, Valent P, Superti-Furga G. Rix U, et al. Among authors: colinge j. Leukemia. 2010 Jan;24(1):44-50. doi: 10.1038/leu.2009.228. Epub 2009 Nov 5. Leukemia. 2010. PMID: 19890374
A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL.
Rix U, Colinge J, Blatt K, Gridling M, Remsing Rix LL, Parapatics K, Cerny-Reiterer S, Burkard TR, Jäger U, Melo JV, Bennett KL, Valent P, Superti-Furga G. Rix U, et al. Among authors: colinge j. PLoS One. 2013 Oct 10;8(10):e77155. doi: 10.1371/journal.pone.0077155. eCollection 2013. PLoS One. 2013. PMID: 24130846 Free PMC article.
The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.
Hantschel O, Rix U, Schmidt U, Bürckstümmer T, Kneidinger M, Schütze G, Colinge J, Bennett KL, Ellmeier W, Valent P, Superti-Furga G. Hantschel O, et al. Among authors: colinge j. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13283-8. doi: 10.1073/pnas.0702654104. Epub 2007 Aug 7. Proc Natl Acad Sci U S A. 2007. PMID: 17684099 Free PMC article.
Charting the molecular network of the drug target Bcr-Abl.
Brehme M, Hantschel O, Colinge J, Kaupe I, Planyavsky M, Köcher T, Mechtler K, Bennett KL, Superti-Furga G. Brehme M, et al. Among authors: colinge j. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7414-9. doi: 10.1073/pnas.0900653106. Epub 2009 Apr 20. Proc Natl Acad Sci U S A. 2009. PMID: 19380743 Free PMC article.
Initial characterization of the human central proteome.
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Bürckstümmer T, Bennett KL, Superti-Furga G, Colinge J. Burkard TR, et al. Among authors: colinge j. BMC Syst Biol. 2011 Jan 26;5:17. doi: 10.1186/1752-0509-5-17. BMC Syst Biol. 2011. PMID: 21269460 Free PMC article.
Systems biology analysis of protein-drug interactions.
Colinge J, Rix U, Bennett KL, Superti-Furga G. Colinge J, et al. Proteomics Clin Appl. 2012 Jan;6(1-2):102-16. doi: 10.1002/prca.201100077. Epub 2011 Dec 27. Proteomics Clin Appl. 2012. PMID: 22213655 Review.
119 results