Sigal NH - Search Results

1

The enzymatic activity of human cytotoxic T-lymphocyte granzyme A and cytolysis mediated by cytotoxic T-lymphocytes are potently inhibited by a synthetic antiprotease, FUT-175.

Poe M, Wu JK, Blake JT, Zweerink HJ, Sigal NH. Poe M, et al. Among authors: sigal nh. Arch Biochem Biophys. 1991 Jan;284(1):215-8. doi: 10.1016/0003-9861(91)90286-r. Arch Biochem Biophys. 1991. PMID: 1989498

2

Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity.

Poe M, Blake JT, Boulton DA, Gammon M, Sigal NH, Wu JK, Zweerink HJ. Poe M, et al. Among authors: sigal nh. J Biol Chem. 1991 Jan 5;266(1):98-103. J Biol Chem. 1991. PMID: 1985927 Free article.

3

Human cytotoxic lymphocyte tryptase. Its purification from granules and the characterization of inhibitor and substrate specificity.

Poe M, Bennett CD, Biddison WE, Blake JT, Norton GP, Rodkey JA, Sigal NH, Turner RV, Wu JK, Zweerink HJ. Poe M, et al. Among authors: sigal nh. J Biol Chem. 1988 Sep 15;263(26):13215-22. J Biol Chem. 1988. PMID: 3047119 Free article.

4

A human monoclonal antibody that protects mice against Pseudomonas-induced pneumonia.

Zweerink HJ, Detolla LJ, Gammon MC, Hutchison CF, Puckett JM, Sigal NH. Zweerink HJ, et al. Among authors: sigal nh. J Infect Dis. 1990 Jul;162(1):254-7. doi: 10.1093/infdis/162.1.254. J Infect Dis. 1990. PMID: 2113078

5

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin.

Siekierka JJ, Hung SH, Poe M, Lin CS, Sigal NH. Siekierka JJ, et al. Among authors: sigal nh. Nature. 1989 Oct 26;341(6244):755-7. doi: 10.1038/341755a0. Nature. 1989. PMID: 2477714

6

X-linked immunodeficient mice as a model for testing the protective efficacy of monoclonal antibodies against Pseudomonas aeruginosa.

Zweerink HJ, Gammon MC, Hutchison CF, Jackson JJ, Pier GB, Puckett JM, Sewell TJ, Sigal NH. Zweerink HJ, et al. Among authors: sigal nh. Infect Immun. 1988 May;56(5):1209-14. doi: 10.1128/iai.56.5.1209-1214.1988. Infect Immun. 1988. PMID: 3128480 Free PMC article.

7

Human monoclonal antibodies that protect mice against challenge with Pseudomonas aeruginosa.

Zweerink HJ, Gammon MC, Hutchison CF, Jackson JJ, Lombardo D, Miner KM, Puckett JM, Sewell TJ, Sigal NH. Zweerink HJ, et al. Among authors: sigal nh. Infect Immun. 1988 Aug;56(8):1873-9. doi: 10.1128/iai.56.8.1873-1879.1988. Infect Immun. 1988. PMID: 3135264 Free PMC article.

8

Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation.

Lin CS, Boltz RC, Blake JT, Nguyen M, Talento A, Fischer PA, Springer MS, Sigal NH, Slaughter RS, Garcia ML, et al. Lin CS, et al. Among authors: sigal nh. J Exp Med. 1993 Mar 1;177(3):637-45. doi: 10.1084/jem.177.3.637. J Exp Med. 1993. PMID: 7679705 Free PMC article.

9

Heterohybridomas that secrete high levels of pseudomonas-specific therapeutic human monoclonal antibodies: their generation and large scale growth in an automated hollow fiber cell culture system.

Gammon MC, Banas MH, Boccumini LE, Sigal NH, Zweerink HJ. Gammon MC, et al. Among authors: sigal nh. Cytotechnology. 1990 Jan;3(1):51-60. doi: 10.1007/BF00365266. Cytotechnology. 1990. PMID: 1367460

10

Blockade of the voltage-gated potassium channel Kv1.3 inhibits immune responses in vivo.

Koo GC, Blake JT, Talento A, Nguyen M, Lin S, Sirotina A, Shah K, Mulvany K, Hora D Jr, Cunningham P, Wunderler DL, McManus OB, Slaughter R, Bugianesi R, Felix J, Garcia M, Williamson J, Kaczorowski G, Sigal NH, Springer MS, Feeney W. Koo GC, et al. Among authors: sigal nh. J Immunol. 1997 Jun 1;158(11):5120-8. J Immunol. 1997. PMID: 9164927

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