Pardo OE - Search Results

1

The fibroblast growth factor receptor inhibitor PD173074 blocks small cell lung cancer growth in vitro and in vivo.

Pardo OE, Latigo J, Jeffery RE, Nye E, Poulsom R, Spencer-Dene B, Lemoine NR, Stamp GW, Aboagye EO, Seckl MJ. Pardo OE, et al. Cancer Res. 2009 Nov 15;69(22):8645-51. doi: 10.1158/0008-5472.CAN-09-1576. Epub 2009 Nov 10. Cancer Res. 2009. PMID: 19903855

2

Asymmetric Dimethylation of Ribosomal S6 Kinase 2 Regulates Its Cellular Localisation and Pro-Survival Function.

Khalil MI, Ismail HM, Panasyuk G, Bdzhola A, Filonenko V, Gout I, Pardo OE. Khalil MI, et al. Among authors: pardo oe. Int J Mol Sci. 2023 May 15;24(10):8806. doi: 10.3390/ijms24108806. Int J Mol Sci. 2023. PMID: 37240151 Free PMC article.

3

Novel cross talk between MEK and S6K2 in FGF-2 induced proliferation of SCLC cells.

Pardo OE, Arcaro A, Salerno G, Tetley TD, Valovka T, Gout I, Seckl MJ. Pardo OE, et al. Oncogene. 2001 Nov 15;20(52):7658-67. doi: 10.1038/sj.onc.1204994. Oncogene. 2001. PMID: 11753643

4

Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis.

Pardo OE, Arcaro A, Salerno G, Raguz S, Downward J, Seckl MJ. Pardo OE, et al. J Biol Chem. 2002 Apr 5;277(14):12040-6. doi: 10.1074/jbc.M109006200. Epub 2002 Jan 28. J Biol Chem. 2002. Retraction in: J Biol Chem. 2015 Jun 19;290(25):15390. doi: 10.1074/jbc.A115.109006 PMID: 11815602 Free article. Retracted.

5

Synthesis and anticancer activity of nordihydroguaiaretic acid (NDGA) and analogues.

McDonald RW, Bunjobpon W, Liu T, Fessler S, Pardo OE, Freer IK, Glaser M, Seckl MJ, Robins DJ. McDonald RW, et al. Among authors: pardo oe. Anticancer Drug Des. 2001 Dec;16(6):261-70. Anticancer Drug Des. 2001. PMID: 12375879

6

Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells.

Pardo OE, Lesay A, Arcaro A, Lopes R, Ng BL, Warne PH, McNeish IA, Tetley TD, Lemoine NR, Mehmet H, Seckl MJ, Downward J. Pardo OE, et al. Mol Cell Biol. 2003 Nov;23(21):7600-10. doi: 10.1128/MCB.23.21.7600-7610.2003. Mol Cell Biol. 2003. PMID: 14560006 Free PMC article.

7

CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness.

Michl P, Ramjaun AR, Pardo OE, Warne PH, Wagner M, Poulsom R, D'Arrigo C, Ryder K, Menke A, Gress T, Downward J. Michl P, et al. Among authors: pardo oe. Cancer Cell. 2005 Jun;7(6):521-32. doi: 10.1016/j.ccr.2005.05.018. Cancer Cell. 2005. PMID: 15950902 Free article.

8

Potent inhibition of small-cell lung cancer cell growth by simvastatin reveals selective functions of Ras isoforms in growth factor signalling.

Khanzada UK, Pardo OE, Meier C, Downward J, Seckl MJ, Arcaro A. Khanzada UK, et al. Among authors: pardo oe. Oncogene. 2006 Feb 9;25(6):877-87. doi: 10.1038/sj.onc.1209117. Oncogene. 2006. PMID: 16170339

9

FGF-2 protects small cell lung cancer cells from apoptosis through a complex involving PKCepsilon, B-Raf and S6K2.

Pardo OE, Wellbrock C, Khanzada UK, Aubert M, Arozarena I, Davidson S, Bowen F, Parker PJ, Filonenko VV, Gout IT, Sebire N, Marais R, Downward J, Seckl MJ. Pardo OE, et al. EMBO J. 2006 Jul 12;25(13):3078-88. doi: 10.1038/sj.emboj.7601198. Epub 2006 Jun 29. EMBO J. 2006. PMID: 16810323 Free PMC article.

10

Yes-associated protein (YAP) functions as a tumor suppressor in breast.

Yuan M, Tomlinson V, Lara R, Holliday D, Chelala C, Harada T, Gangeswaran R, Manson-Bishop C, Smith P, Danovi SA, Pardo O, Crook T, Mein CA, Lemoine NR, Jones LJ, Basu S. Yuan M, et al. Cell Death Differ. 2008 Nov;15(11):1752-9. doi: 10.1038/cdd.2008.108. Epub 2008 Jul 11. Cell Death Differ. 2008. PMID: 18617895

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