Laruelle M - Search Results

1

11C-GSK189254: a selective radioligand for in vivo central nervous system imaging of histamine H3 receptors by PET.

Plisson C, Gunn RN, Cunningham VJ, Bender D, Salinas CA, Medhurst AD, Roberts JC, Laruelle M, Gee AD. Plisson C, et al. Among authors: laruelle m. J Nucl Med. 2009 Dec;50(12):2064-72. doi: 10.2967/jnumed.109.062919. Epub 2009 Nov 12. J Nucl Med. 2009. PMID: 19910432 Free article.

2

Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies.

Bennacef I, Salinas CA, Bonasera TA, Gunn RN, Audrain H, Jakobsen S, Nabulsi N, Weinzimmer D, Carson RE, Huang Y, Holmes I, Micheli F, Heidbreder C, Gentile G, Rossi T, Laruelle M. Bennacef I, et al. Among authors: laruelle m. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5056-9. doi: 10.1016/j.bmcl.2009.07.055. Epub 2009 Jul 25. Bioorg Med Chem Lett. 2009. PMID: 19635669

3

Evaluation of 11C-GSK189254 as a novel radioligand for the H3 receptor in humans using PET.

Ashworth S, Rabiner EA, Gunn RN, Plisson C, Wilson AA, Comley RA, Lai RY, Gee AD, Laruelle M, Cunningham VJ. Ashworth S, et al. Among authors: laruelle m. J Nucl Med. 2010 Jul;51(7):1021-9. doi: 10.2967/jnumed.109.071753. Epub 2010 Jun 16. J Nucl Med. 2010. PMID: 20554726 Free article.

4

Imaging dopamine receptors in humans with [11C]-(+)-PHNO: dissection of D3 signal and anatomy.

Tziortzi AC, Searle GE, Tzimopoulou S, Salinas C, Beaver JD, Jenkinson M, Laruelle M, Rabiner EA, Gunn RN. Tziortzi AC, et al. Among authors: laruelle m. Neuroimage. 2011 Jan 1;54(1):264-77. doi: 10.1016/j.neuroimage.2010.06.044. Epub 2010 Jun 30. Neuroimage. 2011. PMID: 20600980

5

Radiosynthesis and characterization of 11C-GSK215083 as a PET radioligand for the 5-HT6 receptor.

Parker CA, Gunn RN, Rabiner EA, Slifstein M, Comley R, Salinas C, Johnson CN, Jakobsen S, Houle S, Laruelle M, Cunningham VJ, Martarello L. Parker CA, et al. Among authors: laruelle m. J Nucl Med. 2012 Feb;53(2):295-303. doi: 10.2967/jnumed.111.093419. Epub 2012 Jan 5. J Nucl Med. 2012. PMID: 22223878 Free article. Clinical Trial.

6

Human Kinetic Modeling of the 5HT6 PET Radioligand 11C-GSK215083 and Its Utility for Determining Occupancy at Both 5HT6 and 5HT2A Receptors by SB742457 as a Potential Therapeutic Mechanism of Action in Alzheimer Disease.

Parker CA, Rabiner EA, Gunn RN, Searle G, Martarello L, Comley RA, Davy M, Wilson AA, Houle S, Mizrahi R, Laruelle M, Cunningham VJ. Parker CA, et al. Among authors: laruelle m. J Nucl Med. 2015 Dec;56(12):1901-9. doi: 10.2967/jnumed.115.162743. Epub 2015 Sep 17. J Nucl Med. 2015. PMID: 26383152 Free article.

7

Unexpectedly high affinity of a novel histamine H(3) receptor antagonist, GSK239512, in vivo in human brain, determined using PET.

Ashworth S, Berges A, Rabiner EA, Wilson AA, Comley RA, Lai RY, Boardley R, Searle G, Gunn RN, Laruelle M, Cunningham VJ. Ashworth S, et al. Among authors: laruelle m. Br J Pharmacol. 2014 Mar;171(5):1241-9. doi: 10.1111/bph.12505. Br J Pharmacol. 2014. PMID: 24670146 Free PMC article. Clinical Trial.

8

Estimation of serotonin transporter parameters with 11C-DASB in healthy humans: reproducibility and comparison of methods.

Frankle WG, Slifstein M, Gunn RN, Huang Y, Hwang DR, Darr EA, Narendran R, Abi-Dargham A, Laruelle M. Frankle WG, et al. Among authors: laruelle m. J Nucl Med. 2006 May;47(5):815-26. J Nucl Med. 2006. PMID: 16644752 Free article.

9

Kinetic modeling of 11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo.

Marner L, Gillings N, Comley RA, Baaré WF, Rabiner EA, Wilson AA, Houle S, Hasselbalch SG, Svarer C, Gunn RN, Laruelle M, Knudsen GM. Marner L, et al. Among authors: laruelle m. J Nucl Med. 2009 Jun;50(6):900-8. doi: 10.2967/jnumed.108.058552. J Nucl Med. 2009. PMID: 19470850 Free article.

10

Measuring drug occupancy in the absence of a reference region: the Lassen plot re-visited.

Cunningham VJ, Rabiner EA, Slifstein M, Laruelle M, Gunn RN. Cunningham VJ, et al. Among authors: laruelle m. J Cereb Blood Flow Metab. 2010 Jan;30(1):46-50. doi: 10.1038/jcbfm.2009.190. Epub 2009 Sep 9. J Cereb Blood Flow Metab. 2010. PMID: 19738632 Free PMC article.

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