Giles F - Search Results

1

Clinical pharmacokinetics of the BCR-ABL tyrosine kinase inhibitor nilotinib.

Tanaka C, Yin OQ, Sethuraman V, Smith T, Wang X, Grouss K, Kantarjian H, Giles F, Ottmann OG, Galitz L, Schran H. Tanaka C, et al. Among authors: giles f. Clin Pharmacol Ther. 2010 Feb;87(2):197-203. doi: 10.1038/clpt.2009.208. Epub 2009 Nov 18. Clin Pharmacol Ther. 2010. PMID: 19924121 Clinical Trial.

2

Concurrent use of proton pump inhibitors or H2 blockers did not adversely affect nilotinib efficacy in patients with chronic myeloid leukemia.

Yin OQ, Giles FJ, Baccarani M, le Coutre P, Chiparus O, Gallagher N, Saglio G, Hughes TP, Hochhaus A, Kantarjian HM, Larson RA. Yin OQ, et al. Cancer Chemother Pharmacol. 2012 Aug;70(2):345-50. doi: 10.1007/s00280-012-1881-3. Epub 2012 May 24. Cancer Chemother Pharmacol. 2012. PMID: 22623211 Free PMC article.

3

UGT1A1 promoter polymorphism increases risk of nilotinib-induced hyperbilirubinemia.

Singer JB, Shou Y, Giles F, Kantarjian HM, Hsu Y, Robeva AS, Rae P, Weitzman A, Meyer JM, Dugan M, Ottmann OG. Singer JB, et al. Among authors: giles f. Leukemia. 2007 Nov;21(11):2311-5. doi: 10.1038/sj.leu.2404827. Epub 2007 Jul 5. Leukemia. 2007. PMID: 17611564 Clinical Trial.

4

Heterogeneity in detecting Abl kinase mutations and better sensitivity using circulating plasma RNA.

Ma W, Kantarjian H, Jilani I, Gorre M, Bhalla K, Ottmann O, Giles F, Albitar M. Ma W, et al. Among authors: giles f. Leukemia. 2006 Nov;20(11):1989-91. doi: 10.1038/sj.leu.2404355. Epub 2006 Aug 24. Leukemia. 2006. PMID: 16932346

5

Prediction of outcomes in patients with Ph+ chronic myeloid leukemia in chronic phase treated with nilotinib after imatinib resistance/intolerance.

Jabbour E, le Coutre PD, Cortes J, Giles F, Bhalla KN, Pinilla-Ibarz J, Larson RA, Gattermann N, Ottmann OG, Hochhaus A, Hughes TP, Saglio G, Radich JP, Kim DW, Martinelli G, Reynolds J, Woodman RC, Baccarani M, Kantarjian HM. Jabbour E, et al. Among authors: giles f. Leukemia. 2013 Apr;27(4):907-13. doi: 10.1038/leu.2012.305. Epub 2012 Nov 6. Leukemia. 2013. PMID: 23174881 Free PMC article.

6

Frequency and clinical significance of BCR-ABL mutations in patients with chronic myeloid leukemia treated with imatinib mesylate.

Jabbour E, Kantarjian H, Jones D, Talpaz M, Bekele N, O'Brien S, Zhou X, Luthra R, Garcia-Manero G, Giles F, Rios MB, Verstovsek S, Cortes J. Jabbour E, et al. Among authors: giles f. Leukemia. 2006 Oct;20(10):1767-73. doi: 10.1038/sj.leu.2404318. Epub 2006 Jul 20. Leukemia. 2006. PMID: 16855631

7

Three novel alternative splicing mutations in BCR-ABL1 detected in CML patients with resistance to kinase inhibitors.

Ma W, Giles F, Zhang X, Wang X, Zhang Z, Lee TS, Yeh CH, Albitar M. Ma W, et al. Among authors: giles f. Int J Lab Hematol. 2011 Jun;33(3):326-31. doi: 10.1111/j.1751-553X.2010.01291.x. Epub 2011 Jan 26. Int J Lab Hematol. 2011. PMID: 21266020

8

Phase I study of liposomal daunorubicin in patients with acute leukemia.

Cortes J, O'Brien S, Estey E, Giles F, Keating M, Kantarjian H. Cortes J, et al. Among authors: giles f. Invest New Drugs. 1999;17(1):81-7. doi: 10.1023/a:1006216001681. Invest New Drugs. 1999. PMID: 10555126 Clinical Trial.

9

Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia.

Stone RM, Fischer T, Paquette R, Schiller G, Schiffer CA, Ehninger G, Cortes J, Kantarjian HM, DeAngelo DJ, Huntsman-Labed A, Dutreix C, del Corral A, Giles F. Stone RM, et al. Among authors: giles f. Leukemia. 2012 Sep;26(9):2061-8. doi: 10.1038/leu.2012.115. Epub 2012 Apr 27. Leukemia. 2012. PMID: 22627678 Free PMC article. Clinical Trial.

10

Phase I and pharmacologic study of 9-aminocamptothecin colloidal dispersion formulation in patients with refractory or relapsed acute leukemia.

Vey N, Kantarjian H, Tran H, Beran M, O'Brien S, Bivins C, Giles F, Cortes J, Cheson B, Arbuck S, Estey E. Vey N, et al. Among authors: giles f. Ann Oncol. 1999 May;10(5):577-83. doi: 10.1023/a:1026406920321. Ann Oncol. 1999. PMID: 10416008 Free article. Clinical Trial.

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