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A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death.
Atkinson J, Kapralov AA, Yanamala N, Tyurina YY, Amoscato AA, Pearce L, Peterson J, Huang Z, Jiang J, Samhan-Arias AK, Maeda A, Feng W, Wasserloos K, Belikova NA, Tyurin VA, Wang H, Fletcher J, Wang Y, Vlasova II, Klein-Seetharaman J, Stoyanovsky DA, Bayîr H, Pitt BR, Epperly MW, Greenberger JS, Kagan VE. Atkinson J, et al. Among authors: huang z. Nat Commun. 2011 Oct 11;2:497. doi: 10.1038/ncomms1499. Nat Commun. 2011. PMID: 21988913 Free PMC article.
Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids.
Jiang J, Bakan A, Kapralov AA, Ishara Silva K, Huang Z, Amoscato AA, Peterson J, Krishna Garapati V, Saxena S, Bayir H, Atkinson J, Bahar I, Kagan VE. Jiang J, et al. Among authors: huang z. Free Radic Biol Med. 2014 Jun;71:221-230. doi: 10.1016/j.freeradbiomed.2014.02.029. Epub 2014 Mar 12. Free Radic Biol Med. 2014. PMID: 24631490 Free PMC article.
Necrostatin-1 rescues mice from lethal irradiation.
Huang Z, Epperly M, Watkins SC, Greenberger JS, Kagan VE, Bayır H. Huang Z, et al. Biochim Biophys Acta. 2016 Apr;1862(4):850-856. doi: 10.1016/j.bbadis.2016.01.014. Epub 2016 Jan 20. Biochim Biophys Acta. 2016. PMID: 26802452 Free PMC article.
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