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Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.
Vendrame F, Pileggi A, Laughlin E, Allende G, Martin-Pagola A, Molano RD, Diamantopoulos S, Standifer N, Geubtner K, Falk BA, Ichii H, Takahashi H, Snowhite I, Chen Z, Mendez A, Chen L, Sageshima J, Ruiz P, Ciancio G, Ricordi C, Reijonen H, Nepom GT, Burke GW 3rd, Pugliese A. Vendrame F, et al. Among authors: reijonen h. Diabetes. 2010 Apr;59(4):947-57. doi: 10.2337/db09-0498. Epub 2010 Jan 19. Diabetes. 2010. PMID: 20086230 Free PMC article.
Low-avidity recognition by CD4+ T cells directed to self-antigens.
Gebe JA, Falk BA, Rock KA, Kochik SA, Heninger AK, Reijonen H, Kwok WW, Nepom GT. Gebe JA, et al. Among authors: reijonen h. Eur J Immunol. 2003 May;33(5):1409-17. doi: 10.1002/eji.200323871. Eur J Immunol. 2003. PMID: 12731068 Free article.
Insulin protein and proliferation in ductal cells in the transplanted pancreas of patients with type 1 diabetes and recurrence of autoimmunity.
Martin-Pagola A, Sisino G, Allende G, Dominguez-Bendala J, Gianani R, Reijonen H, Nepom GT, Ricordi C, Ruiz P, Sageshima J, Ciancio G, Burke GW, Pugliese A. Martin-Pagola A, et al. Among authors: reijonen h. Diabetologia. 2008 Oct;51(10):1803-13. doi: 10.1007/s00125-008-1105-x. Epub 2008 Aug 12. Diabetologia. 2008. PMID: 18696047 Free PMC article.
94 results