Fu W - Search Results

1

Highly selective and potent mu opioid ligands by unexpected substituent on morphine skeleton.

Li W, Tao YM, Tang Y, Xu XJ, Chen J, Fu W, Wang XH, Chao B, Sheng W, Xie Q, Qiu ZB, Liu JG. Li W, et al. Among authors: fu w. Bioorg Med Chem Lett. 2010 Jan 1;20(1):418-21. doi: 10.1016/j.bmcl.2009.07.119. Epub 2009 Jul 29. Bioorg Med Chem Lett. 2010. PMID: 19932964

2

3-Arylamino-2H-1,2,4-benzothiadiazin-5-ol 1,1-dioxides as novel and selective CXCR2 antagonists.

Wang Y, Busch-Petersen J, Wang F, Ma L, Fu W, Kerns JK, Jin J, Palovich MR, Shen JK, Burman M, Foley JJ, Schmidt DB, Hunsberger GE, Sarau HM, Widdowson KL. Wang Y, et al. Among authors: fu w. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3864-7. doi: 10.1016/j.bmcl.2007.05.011. Epub 2007 May 10. Bioorg Med Chem Lett. 2007. PMID: 17524641

3

Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on amyloid-beta aggregation.

Xie Q, Wang H, Xia Z, Lu M, Zhang W, Wang X, Fu W, Tang Y, Sheng W, Li W, Zhou W, Zhu X, Qiu Z, Chen H. Xie Q, et al. Among authors: fu w. J Med Chem. 2008 Apr 10;51(7):2027-36. doi: 10.1021/jm070154q. Epub 2008 Mar 12. J Med Chem. 2008. PMID: 18333606

4

The crystal structure of a complex of acetylcholinesterase with a bis-(-)-nor-meptazinol derivative reveals disruption of the catalytic triad.

Paz A, Xie Q, Greenblatt HM, Fu W, Tang Y, Silman I, Qiu Z, Sussman JL. Paz A, et al. Among authors: fu w. J Med Chem. 2009 Apr 23;52(8):2543-9. doi: 10.1021/jm801657v. J Med Chem. 2009. PMID: 19326912

5

Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase.

Ma K, Wang P, Fu W, Wan X, Zhou L, Chu Y, Ye D. Ma K, et al. Among authors: fu w. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6724-7. doi: 10.1016/j.bmcl.2011.09.054. Epub 2011 Sep 20. Bioorg Med Chem Lett. 2011. PMID: 21996518

6

Molecular insights into the D1R agonist and D2R/D3R antagonist effects of the natural product (-)-stepholidine: molecular modeling and dynamics simulations.

Li B, Li W, Du P, Yu KQ, Fu W. Li B, et al. Among authors: fu w. J Phys Chem B. 2012 Jul 19;116(28):8121-30. doi: 10.1021/jp3049235. Epub 2012 Jul 3. J Phys Chem B. 2012. PMID: 22702398

7

A computational perspective on drug discovery and signal transduction mechanism of dopamine and serotonin receptors in the treatment of schizophrenia.

Lian P, Xu L, Geng C, Qian Y, Li W, Zhen X, Fu W. Lian P, et al. Among authors: fu w. Curr Pharm Biotechnol. 2014;15(10):916-26. doi: 10.2174/1389201015666140909150033. Curr Pharm Biotechnol. 2014. PMID: 25213308 Review.

8

Design, synthesis and biological evaluation of N-phenylalkyl-substituted tramadol derivatives as novel μ opioid receptor ligands.

Shen Q, Qian YY, Xu XJ, Li W, Liu JG, Fu W. Shen Q, et al. Among authors: fu w. Acta Pharmacol Sin. 2015 Jul;36(7):887-94. doi: 10.1038/aps.2014.171. Epub 2015 Jun 8. Acta Pharmacol Sin. 2015. PMID: 26051109 Free PMC article.

9

Discovery of novel potent and selective ligands for 5-HT2A receptor with quinazoline scaffold.

Deng X, Guo L, Xu L, Zhen X, Yu K, Zhao W, Fu W. Deng X, et al. Among authors: fu w. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3970-4. doi: 10.1016/j.bmcl.2015.07.030. Epub 2015 Jul 18. Bioorg Med Chem Lett. 2015. PMID: 26227779

10

Discovery of Potent and Selective Agonists of δ Opioid Receptor by Revisiting the "Message-Address" Concept.

Shen Q, Qian Y, Huang X, Xu X, Li W, Liu J, Fu W. Shen Q, et al. Among authors: fu w. ACS Med Chem Lett. 2016 Feb 10;7(4):391-6. doi: 10.1021/acsmedchemlett.5b00423. eCollection 2016 Apr 14. ACS Med Chem Lett. 2016. PMID: 27096047 Free PMC article.

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